Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | VDR | P11473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12807579 | 0.91 | MEN1 (0.44) | MAPTALDH1A1TP53TSHRHPGD | |
| SCHEMBL16716239 | 0.90 | ALDH1A1 (0.64) | MAPTALDH1A1TP53TSHRHPGD | |
| SCHEMBL15814648 | 0.90 | ALDH1A1 (0.64) | MAPTALDH1A1TP53TSHRHPGD | |
| SCHEMBL29361272 | 0.89 | ALDH1A1 (0.52) | MAPTALDH1A1TP53TSHRHPGD | |
| SCHEMBL29651825 | 0.89 | ALDH1A1 (0.52) | MAPTALDH1A1TP53TSHRHPGD | |
| SCHEMBL15964084 | 0.89 | ALDH1A1 (0.52) | MAPTALDH1A1TP53TSHRHPGD | |
| SCHEMBL15215823 | 0.89 | ALDH1A1 (0.52) | MAPTALDH1A1TP53TSHRHPGD | |
| SCHEMBL194491 | 0.89 | ALDH1A1 (0.52) | MAPTALDH1A1TP53TSHRHPGD | |
| SCHEMBL2741233 | 0.89 | MAPT (0.44) | MAPTALDH1A1TP53TSHRHPGD | |
| SCHEMBL10038932 | 0.88 | ALDH1A1 (0.54) | MAPTALDH1A1TP53TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8378148-B2 | Alcoholic hydroxyl-containing compounds and making method | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-02-19 | — | — | US | disclosed |
| US-8378148-B2 | Alcoholic hydroxyl-containing compounds and making method | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-02-19 | — | — | US | disclosed |
| EP-2316810-B1 | Alcoholic hydroxyl-containing compounds and making method | SHINETSU CHEMICAL CO (JP) | 2012-01-04 | — | — | EP | disclosed |
| EP-2316810-A1 | Alcoholic hydroxyl-containing compounds and making method | Shin-Etsu Chemical Co., Ltd. (JP) | 2011-05-04 | — | — | EP | disclosed |
| EP-2316810-A1 | Alcoholic hydroxyl-containing compounds and making method | Shin-Etsu Chemical Co., Ltd. (JP) | 2011-05-04 | — | — | EP | disclosed |
| US-20110082321-A1 | ALCOHOLIC HYDROXYL-CONTAINING COMPOUNDS AND MAKING METHOD | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2011-04-07 | — | — | US | disclosed |
| US-20110082321-A1 | ALCOHOLIC HYDROXYL-CONTAINING COMPOUNDS AND MAKING METHOD | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2011-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110082321-A1 | ALCOHOLIC HYDROXYL-CONTAINING COMPOUNDS AND MAKING METHOD | ADH1A, ADH1C, ADH5 | MAPT 2906/4885ALDH1A1 65/4885TP53 2081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.