SCHEMBL1942983

SCHEMBL1942983

O=P(O)(O)c1ccc(-c2ccccc2)c(-c2ccccc2)c1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.52
CA4 P22748 1/20 0.52
CA5A P35218 1/20 0.52
FBP1 P09467 2/20 0.46
GPR84 Q9NQS5 1/20 0.42
BACE1 P56817 1/20 0.41
ALOX5 P09917 1/20 0.41
PGK1 P00558 3/20 0.41
PGK2 P07205 3/20 0.41
KDM4E B2RXH2 1/20 0.40
POLB P06746 1/20 0.40
GRIK1 P39086 1/20 0.39
CFTR P13569 1/20 0.38
PTGS2 P35354 2/20 0.37
ESR2 Q92731 1/20 0.37
ACP3 P15309 1/20 0.37
PTPN1 P18031 1/20 0.37
PTPN5 P54829 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2171470 0.96 CA2 (0.54) CA2CA4CA5AFBP1GPR84
SCHEMBL28899906 0.83 CA2 (0.62) CA2CA4CA5AFBP1GPR84
SCHEMBL3038384 0.82 CA2 (0.56) CA2CA4CA5AFBP1GPR84
SCHEMBL28421469 0.79 CA2 (0.61) CA2CA4CA5APGK1PGK2
SCHEMBL753791 0.76 CA2 (0.71) CA2CA4CA5ACFTRACP3
SCHEMBL26185636 0.76 CA2 (0.50) CA2CA4CA5AFBP1GPR84
Phosphoric Acid SCHEMBL28234428 0.76 ALOX5 (0.61) GPR84BACE1ALOX5KDM4EPOLB
SCHEMBL8921527 0.76 L3MBTL1 (0.43) KDM4E
Phosphoric Acid SCHEMBL29542627 0.75 ALDH1A1 (0.52) CA2CA4CA5AGPR84BACE1
Phosphoric Acid SCHEMBL1281473 0.75 ALDH1A1 (0.52) CA2CA4CA5AGPR84BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9458019-B2 Graphite layers UNIVERSITÄT BIELEFELD (DE) 2016-10-04 US disclosed
EP-2188212-B1 METHOD TO PRODUCE GRAPHENE LAYERS UNIVERSITÄT BIELEFELD (DE) 2015-12-02 EP disclosed
US-20150274530-A1 Graphite Layers UNIVERSITÄT BIELEFELD (DE) 2015-10-01 US disclosed
EP-2032501-B1 NANO-MICROPHONE OR PRESSURE SENSOR UNIV BIELEFELD (DE) 2011-06-15 EP disclosed
US-20100209330-A1 Graphite Layers UNIVERSITAT BIELEFELD (DE) 2010-08-19 US disclosed
EP-2188212-A1 GRAPHITE LAYERS Universität Bielefeld (DE) 2010-05-26 EP disclosed
WO-2009030473-A1 GRAPHITE LAYERS UNIVERSITÄT BIELEFELD (DE) 2009-03-12 WO disclosed
EP-2032501-A2 NANO-MICROPHONE OR PRESSURE SENSOR Universität Bielefeld (DE) 2009-03-11 EP disclosed
EP-1222498-B1 SURFACE-MODIFIED LAYER SYSTEM UNIV HEIDELBERG (DE) 2008-12-03 EP disclosed
WO-2007147643-A2 NANO-MICROPHONE OR PRESSURE SENSOR UNIVERSITÄT BIELEFELD (DE) 2007-12-27 WO disclosed
US-6764758-B1 Surface-modified layer system UNIVERSITAT HEIDELBERG (DE) 2004-07-20 US disclosed
EP-1222498-A2 SURFACE-MODIFIED LAYER SYSTEM Universität Heidelberg (DE) 2002-07-17 EP disclosed
WO-2001023962-A2 SURFACE-MODIFIED LAYER SYSTEM Universität Heidelberg (DE) 2001-04-05 WO disclosed