SCHEMBL19432834

SCHEMBL19432834

O=C(O)C(F)(F)C(F)(F)C(F)(F)C(=O)Oc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ ELANE P08246 4/20 0.42
▸ VCAM1 P19320 1/20 0.42
▸ MAOB P27338 1/20 0.41
▸ ATM Q13315 2/20 0.39
▸ L3MBTL1 Q9Y468 2/20 0.39
▸ TDP1 Q9NUW8 2/20 0.39
▸ HPGD P15428 1/20 0.38
▸ ALOX15 P16050 1/20 0.38
▸ HSD17B10 Q99714 1/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ THRB P10828 1/20 0.38
▸ KDM4E B2RXH2 1/20 0.36
▸ MAPT P10636 1/20 0.36
▸ NSD2 O96028 1/20 0.36
▸ HDAC1 Q13547 1/20 0.36
▸ HDAC2 Q92769 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24360919 0.89 ELANE (0.45) ELANEMAOBATML3MBTL1TDP1
SCHEMBL11924477 0.89 ELANE (0.43) ELANEMAOBATML3MBTL1TDP1
SCHEMBL27845557 0.87 ELANE (0.42) ELANEMAOBATML3MBTL1TDP1
SCHEMBL24361172 0.86 VCAM1 (0.40) ELANEVCAM1ATMALOX15THRB
SCHEMBL24360875 0.84 VCAM1 (0.39) ELANEVCAM1THRBHDAC1
SCHEMBL26061847 0.84 ELANE (0.47) ELANEMAOBATML3MBTL1TDP1
SCHEMBL10187806 0.82 ELANE (0.44) ELANEMAOBATML3MBTL1TDP1
SCHEMBL24360911 0.82 MAPT (0.50) ELANEVCAM1ATML3MBTL1TDP1
SCHEMBL24361894 0.79 TTR (0.42) ELANEVCAM1L3MBTL1ALDH1A1MAPT
SCHEMBL1255890 0.78 ELANE (0.47) ELANEMAOBATML3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220127225-A1 ONIUM SALT, CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-04-28 — — US disclosed
US-20170285469-A1 RESIST COMPOSITION AND METHOD FOR FORMING RESIST PATTERN TOKYO OHKA KOGYO, CO., LTD. (JP) 2017-10-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220127225-A1 ONIUM SALT, CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERNING PROCESS CACNA1F, SLC6A5, IDUA ELANE 3192/4885VCAM1 3719/4885MAOB 3859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback