SCHEMBL194336

SCHEMBL194336

[CH2]COc1ccc(O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 5/20 0.52
LMNA P02545 2/20 0.52
HIF1A Q16665 2/20 0.52
CYP1A2 P05177 1/20 0.52
PTGS1 P23219 1/20 0.52
SLC6A2 P23975 1/20 0.52
CYP2C19 P33261 1/20 0.52
PTGS2 P35354 1/20 0.52
SLC6A3 Q01959 1/20 0.52
HDAC6 Q9UBN7 1/20 0.52
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
ESR1 P03372 1/20 0.50
ESR2 Q92731 1/20 0.50
APP P05067 2/20 0.48
NR5A1 Q13285 1/20 0.48
DRD2 P14416 1/20 0.42
DRD4 P21917 1/20 0.42
DRD3 P35462 1/20 0.42
PTPN1 P18031 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4707838 0.86 NQO1 (0.47) LTA4HLMNAHIF1ACYP1A2PTGS1
SCHEMBL7747278 0.81 KMT2A (0.47) LMNACYP1A2CYP2C19MEN1KMT2A
SCHEMBL73303 0.80 LTA4H (0.55) LTA4HLMNAHIF1ACYP1A2PTGS1
SCHEMBL8452874 0.78 LTA4H (0.56) LTA4HLMNAHIF1ACYP1A2PTGS1
SCHEMBL226548 0.78 LTA4H (0.64) LTA4HLMNAHIF1ACYP1A2PTGS1
SCHEMBL7465840 0.77 NR5A1 (0.62) LTA4HLMNAHIF1ACYP1A2PTGS1
SCHEMBL2470706 0.76 NR5A1 (0.75) LTA4HLMNAHIF1ACYP1A2PTGS1
SCHEMBL2473527 0.76 LTA4H (0.68) LTA4HLMNAHIF1ACYP1A2PTGS1
SCHEMBL4537440 0.76 LTA4H (0.54) LTA4HLMNAHIF1ACYP1A2PTGS1
SCHEMBL2803702 0.75 ALDH1A1 (0.60) LMNAMEN1KMT2AAPPCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3985726-A DYEING AND PRINTING LEATHER, WOOL, SILK AND SYNTHETIC FIBERS CIBA-GEIGY AG (CH) 1976-10-12 US claimed
US-3971740-A DYES FOR POLYESTER FIBERS CIBA-GEIGY AG (CH) 1976-07-27 US claimed
US-3933800-A O-SUBSTITUTED OXIMES, MICROBIOCIDES GRUPPO LEPETIT S.P.A. (IT) 1976-01-20 US claimed
US-20240182463-A1 SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG SHIONOGI & CO., LTD. (JP) 2024-06-06 US disclosed
US-20230117695-A1 ARENAVIRUS GROWTH INHIBITOR COMPRISING POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2023-04-20 US disclosed
US-11492352-B2 Arenavirus growth inhibitor comprising polycyclic carbamoylpyridone derivative NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2022-11-08 US disclosed
US-11209733-B2 Oxime ester photoinitiators BASF SE 2021-12-28 US disclosed
US-11209734-B2 Oxime ester photoinitiators BASF SE 2021-12-28 US disclosed
US-11204554-B2 Oxime ester photoinitiators BASF SE 2021-12-21 US disclosed
US-20210292321-A1 ARENAVIRUS GROWTH INHIBITOR COMPRISING POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2021-09-23 US disclosed
EP-3815689-A1 ARENAVIRUS GROWTH INHIBITOR COMPRISING POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE National University Corporation Hokkaido University (JP) 2021-05-05 EP disclosed
CN-1104412-A Peripheral Vasodilating agent containing N-acylated 4-amino piperidine derivatives as active ingredients OTSUKA PHARMA CO LTD (JP) 1995-06-28 CN disclosed
EP-0650476-A1 PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1995-05-03 EP disclosed
WO-1994022826-A1 PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1994-10-13 WO disclosed
US-4179435-A SULPHONIC ACID-FREE CIBA-GEIGY CORPORATION (US) 1979-12-18 US disclosed
US-4115381-A FOR POLYESTER FIBERS CIBA-GEIGY CORPORATION (US) 1978-09-19 US disclosed
US-4014864-A POLYESTER FIBERS CIBA-GEIGY CORPORATION (US) 1977-03-29 US disclosed
US-3971740-A DYES FOR POLYESTER FIBERS CIBA-GEIGY AG (CH) 1976-07-27 US disclosed
US-3945989-A Fluoro triazine containing water insoluble azo dyestuff CIBA-GEIGY AG (CH) 1976-03-23 US disclosed
US-3943120-A WATER INSOLUBLE CIBA-GEIGY AG (CH) 1976-03-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11492352-B2 Arenavirus growth inhibitor comprising polycyclic carbamoylpyridone derivative LUC7L2, CXCR6, RRP12 LTA4H 1148/4885LMNA 2906/4885HIF1A 2867/4885
US-20240182463-A1 SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG PREP, UNG, DPP4 LTA4H 2134/4885LMNA 1238/4885HIF1A 933/4885
US-11209734-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 LTA4H 996/4885LMNA 2575/4885HIF1A 1305/4885
US-11204554-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 LTA4H 1014/4885LMNA 2745/4885HIF1A 1358/4885
US-20230117695-A1 ARENAVIRUS GROWTH INHIBITOR COMPRISING POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE CDK7, CCNA1, CCR10 LTA4H 747/4885LMNA 1927/4885HIF1A 3510/4885
US-20210292321-A1 ARENAVIRUS GROWTH INHIBITOR COMPRISING POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE CCNA1, CDK7, CCR10 LTA4H 932/4885LMNA 2054/4885HIF1A 3394/4885
US-11209733-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 LTA4H 996/4885LMNA 2575/4885HIF1A 1305/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.