Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16106244 | 0.85 | ALDH1A1 (0.49) | ALDH1A1LMNAMAPTHPGDKMT2A | |
| SCHEMBL16106495 | 0.85 | ALDH1A1 (0.49) | ALDH1A1LMNAMAPTHPGDKMT2A | |
| SCHEMBL16150299 | 0.85 | ALDH1A1 (0.49) | ALDH1A1LMNAMAPTHPGDKMT2A | |
| SCHEMBL15720675 | 0.82 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPTHPGDKMT2A | |
| SCHEMBL15720161 | 0.80 | CHRNB2 (0.56) | ALDH1A1LMNAMAPTHPGDKMT2A | |
| SCHEMBL19434594 | 0.79 | TSHR (0.36) | ALDH1A1MAPTMAPK1 | |
| SCHEMBL15721030 | 0.79 | VCAM1 (0.51) | ALDH1A1LMNAMAPTHPGDKMT2A | |
| SCHEMBL16106578 | 0.79 | MEN1 (0.45) | ALDH1A1LMNAMAPTHPGDKMT2A | |
| SCHEMBL19434601 | 0.75 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPTHPGDKMT2A | |
| SCHEMBL5203318 | 0.75 | VCAM1 (0.50) | LMNAMAPTKMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3440073-B1 | KINASE INHIBITORS | OXULAR ACQUISITIONS LTD (GB) | 2022-06-08 | — | — | EP | disclosed |
| US-10442828-B2 | Kinase inhibitors | TOPIVERT PHARMA LIMITED (GB) | 2019-10-15 | — | — | US | disclosed |
| EP-3440073-A1 | KINASE INHIBITORS | Topivert Pharma Limited (GB) | 2019-02-13 | — | — | EP | disclosed |
| US-20180305383-A1 | KINASE INHIBITORS | OXULAR ACQUISITIONS LIMITED (GB) | 2018-10-25 | — | — | US | disclosed |
| US-10072034-B2 | Kinase inhibitors | RESPIVERT LIMITED (GB) | 2018-09-11 | — | — | US | disclosed |
| US-20170291917-A1 | KINASE INHIBITORS | OXULAR ACQUISITIONS LIMITED (GB) | 2017-10-12 | — | — | US | disclosed |
| WO-2017174995-A1 | KINASE INHIBITORS | RESPIVERT LIMITED (GB) | 2017-10-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10072034-B2 | Kinase inhibitors | SYK, LYN, BTK | ALDH1A1 4786/4885LMNA 4562/4885MAPT 3513/4885 |
| US-20180305383-A1 | KINASE INHIBITORS | SYK, LTK, LTB4R | ALDH1A1 4550/4885LMNA 4232/4885MAPT 4612/4885 |
| US-10442828-B2 | Kinase inhibitors | SYK, LTK, LTB4R | ALDH1A1 4550/4885LMNA 4232/4885MAPT 4612/4885 |
| US-20170291917-A1 | KINASE INHIBITORS | SYK, LYN, BTK | ALDH1A1 4786/4885LMNA 4562/4885MAPT 3513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.