SCHEMBL1944111

SCHEMBL1944111

O=C(C(=O)c1ccccc1Oc1ccc(Oc2ccccc2C(=O)C(=O)c2ccccc2)c2ccccc12)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 10/20 0.48
CES1 P23141 9/20 0.48
HTT P42858 1/20 0.45
CTNNB1 P35222 1/20 0.42
SRC P12931 1/20 0.42
TGFBR1 P36897 1/20 0.42
MEN1 O00255 1/20 0.41
JAK2 O60674 1/20 0.41
USP2 O75604 1/20 0.41
ESR1 P03372 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
ALOX15 P16050 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
ESR2 Q92731 1/20 0.41
HSD17B10 Q99714 1/20 0.41
ADORA1 P30542 1/20 0.40
CDC25B P30305 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4197049 0.91 CES2 (0.58) CES2CES1HTTCTNNB1MAPT
SCHEMBL4579639 0.86 HTT (0.61) CES2CES1HTTCTNNB1MEN1
SCHEMBL11508105 0.82 CTNNB1 (0.62) CES2CES1HTTCTNNB1MEN1
SCHEMBL6832601 0.78 CES2 (0.56) CES2CES1CTNNB1MAPTKMT2A
SCHEMBL6130408 0.78 MEN1 (0.51) CES2CES1CTNNB1MEN1GAA
Benzil SCHEMBL6674970 0.77 CES2 (0.58) CES2CES1CTNNB1
SCHEMBL27546791 0.77 CES2 (0.56) CES2CES1CTNNB1MEN1MAPT
SCHEMBL5704292 0.77 RAB9A (0.62) CES2CES1HTTMAPTKMT2A
SCHEMBL28209709 0.76 CTNNB1 (0.54) CES2CES1CTNNB1MEN1MAPT
SCHEMBL6863551 0.75 CES2 (0.52) CES2CES1MAPTKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1900541-B1 Heat-sensitive recording material and production method thereof RICOH CO LTD (JP) 2014-08-13 EP disclosed
US-8168565-B2 Thermal recording adhesive label RICOH COMPANY, LTD. (JP) 2012-05-01 US disclosed
US-8147905-B2 Heat-sensitive recording material and production method thereof RICOH COMPANY, LTD. (JP) 2012-04-03 US disclosed
US-20110135830-A1 HEAT-SENSITIVE RECORDING MATERIAL AND PRODUCTION METHOD THEREOF RICOH COMPANY, LTD. (JP) 2011-06-09 US disclosed
US-7906458-B2 Color developing layer on a substrate, containing a leuco dye and a developer; protective layer of a binder resin, of diacetone-modified polyvinyl alcohol resin RICOH COMPANY, LTD. (JP) 2011-03-15 US disclosed
US-20090209419-A1 THERMAL RECORDING ADHESIVE LABEL RICOH COMPANY, LTD. (JP) 2009-08-20 US disclosed
US-20080146443-A1 Heat-sensitive recording material and production method thereof RICOH COMPANY, LTD. (JP) 2008-06-19 US disclosed
EP-1900541-A1 Heat-sensitive recording material and production method thereof RICOH Co., Ltd. (JP) 2008-03-19 EP disclosed
EP-1243437-B1 Leuco dye dispersion liquid and thermosensitive recording material using the same RICOH KK (JP) 2004-11-17 EP disclosed