Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 13/20 | 0.38 |
| ▸ | NPY1R | P25929 | 9/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.38 |
| ▸ | NPY2R | P49146 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17949771 | 0.88 | HTR2A (0.41) | NPY4RNPY1RNPY5RNPY2RALDH1A1 | |
| SCHEMBL19445675 | 0.86 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL10261740 | 0.86 | NPY4R (0.44) | NPY4RNPY1RNPY5RNPY2RKCNB1 | |
| SCHEMBL15277771 | 0.82 | NPY4R (0.42) | NPY4RNPY1RNPY5RNPY2RKCNB1 | |
| SCHEMBL14655196 | 0.82 | LMNA (0.35) | NPY4RNPY1RNPY5RNPY2RALDH1A1 | |
| SCHEMBL13973705 | 0.81 | NPY4R (0.39) | NPY4RNPY1RNPY5RNPY2RKCNA5 | |
| SCHEMBL15277770 | 0.81 | MMP2 (0.41) | NPY4RNPY1RKCNA5KCNH2KCNB1 | |
| SCHEMBL12515508 | 0.81 | ALDH1A1 (0.41) | NPY4RNPY1RALDH1A1KCNB1 | |
| SCHEMBL13973757 | 0.81 | MMP2 (0.41) | NPY4RNPY1RKCNA5KCNH2KCNB1 | |
| SCHEMBL10262220 | 0.81 | ALDH1A1 (0.41) | NPY4RNPY1RALDH1A1KCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2709619-B1 | COMPOUNDS FOR USE IN TREATMENT OF MUCOSITIS | CELLCEUTIX CORP (US) | 2017-10-11 | — | — | EP | disclosed |