Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.34 |
| ▸ | NPY4R | P50391 | 5/20 | 0.33 |
| ▸ | NPY1R | P25929 | 4/20 | 0.33 |
| ▸ | NPY2R | P49146 | 3/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19445501 | 0.82 | NPY4R (0.38) | ALDH1A1TAS1R3TAS1R1NPY4RNPY1R | |
| SCHEMBL19445675 | 0.79 | ALDH1A1 (0.43) | LMNAALDH1A1GAAKDM4EPOLB | |
| SCHEMBL19445176 | 0.78 | LMNA (0.41) | LMNAALDH1A1POLB | |
| SCHEMBL15277771 | 0.77 | NPY4R (0.42) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL13973705 | 0.76 | NPY4R (0.39) | LMNANPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL17949771 | 0.76 | HTR2A (0.41) | ALDH1A1TAS1R3TAS1R1NPY4RNPY1R | |
| SCHEMBL14655194 | 0.76 | ITGB3 (0.36) | LMNATAS1R3TAS1R1MAPT | |
| SCHEMBL12515508 | 0.76 | ALDH1A1 (0.41) | LMNAALDH1A1NPY4RNPY1RPOLB | |
| SCHEMBL15277770 | 0.76 | MMP2 (0.41) | LMNANPY4RNPY1RMAPT | |
| SCHEMBL10262220 | 0.76 | ALDH1A1 (0.41) | LMNAALDH1A1NPY4RNPY1RPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130023561-A1 | Facially Amphiphilic Polymers and Oligomers and Uses Thereof | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2013-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130023561-A1 | Facially Amphiphilic Polymers and Oligomers and Uses Thereof | TLR3, ABHD16A, ANTXR2 | LMNA 1283/4885ALDH1A1 4843/4885TAS1R3 151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.