Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 8/20 | 0.44 |
| ▸ | LNPEP | Q9UIQ6 | 7/20 | 0.44 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.43 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19445695 | 0.95 | SUV39H2 (0.45) | ERAP2LNPEPERAP1SUV39H2LTA4H | |
| SCHEMBL19445595 | 0.94 | SUV39H2 (0.45) | ERAP2LNPEPERAP1SUV39H2LTA4H | |
| SCHEMBL19445810 | 0.92 | KCNB1 (0.40) | ERAP2LNPEPERAP1KLKB1MMP2 | |
| SCHEMBL19445879 | 0.91 | KCNK3 (0.41) | KLKB1MMP2 | |
| SCHEMBL19445603 | 0.91 | KLKB1 (0.39) | ERAP2LNPEPERAP1KLKB1MMP2 | |
| SCHEMBL13962658 | 0.90 | ERAP2 (0.47) | ERAP2LNPEPERAP1SUV39H2LTA4H | |
| SCHEMBL12766953 | 0.90 | ERAP2 (0.47) | ERAP2LNPEPERAP1SUV39H2LTA4H | |
| SCHEMBL19445834 | 0.90 | MMP2 (0.39) | SUV39H2KLKB1MMP2 | |
| SCHEMBL19445644 | 0.89 | ERAP2 (0.44) | ERAP2LNPEPERAP1SUV39H2LTA4H | |
| SCHEMBL19445813 | 0.89 | ERAP2 (0.47) | ERAP2LNPEPERAP1SUV39H2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2709619-B1 | COMPOUNDS FOR USE IN TREATMENT OF MUCOSITIS | CELLCEUTIX CORP (US) | 2017-10-11 | — | — | EP | disclosed |