SCHEMBL19445834 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	MMP2	P08253	5/20	0.39

▸	KLKB1	P03952	1/20	0.38

▸	TSHR	P16473	1/20	0.38

▸	HPGDS	O60760	1/20	0.37

▸	KCNB1	Q14721	2/20	0.36

▸	HDAC1	Q13547	1/20	0.35

▸	CAPN1	P07384	1/20	0.35

▸	KMT2A	Q03164	2/20	0.35

▸	SUV39H2	Q9H5I1	1/20	0.35

▸	PDF	Q9HBH1	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL12516946	0.93	KLKB1 (0.42)	MMP2KLKB1TSHRHPGDSKCNB1
SCHEMBL19445833	0.93	KLKB1 (0.42)	MMP2KLKB1TSHRHPGDSKCNB1
SCHEMBL19445810	0.90	KCNB1 (0.40)	MMP2KLKB1TSHRKCNB1HDAC1
SCHEMBL19445603	0.90	KLKB1 (0.39)	MMP2KLKB1TSHRKCNB1HDAC1
SCHEMBL19445879	0.90	KCNK3 (0.41)	MMP2KLKB1TSHRKCNB1HDAC1
SCHEMBL19445641	0.90	ERAP2 (0.44)	MMP2KLKB1SUV39H2
SCHEMBL13977753	0.89	KLKB1 (0.40)	MMP2KLKB1TSHRHPGDSKCNB1
SCHEMBL12779221	0.86	ERAP2 (0.47)	MMP2KLKB1TSHRHPGDSSUV39H2
SCHEMBL19445695	0.85	SUV39H2 (0.45)	MMP2KCNB1SUV39H2
SCHEMBL19944963	0.84	HPGDS (0.48)	MMP2KLKB1TSHRHPGDSKCNB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2709619-B1	COMPOUNDS FOR USE IN TREATMENT OF MUCOSITIS	CELLCEUTIX CORP (US)	2017-10-11	—	—	EP	disclosed