Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 3/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19445810 | 0.92 | KCNB1 (0.40) | TSHRHDAC1KLKB1MMP2KCNB1 | |
| SCHEMBL19445641 | 0.91 | ERAP2 (0.44) | KLKB1MMP2 | |
| SCHEMBL19445603 | 0.91 | KLKB1 (0.39) | TSHRHDAC1KLKB1MMP2KCNB1 | |
| SCHEMBL19445834 | 0.90 | MMP2 (0.39) | TSHRKMT2AHDAC1CAPN1KLKB1 | |
| SCHEMBL19445695 | 0.86 | SUV39H2 (0.45) | MMP2KCNB1 | |
| SCHEMBL19445595 | 0.85 | SUV39H2 (0.45) | MMP2KCNB1 | |
| SCHEMBL19445611 | 0.85 | NPC1 (0.38) | TSHRHDAC1KLKB1MMP2KCNB1 | |
| SCHEMBL19445718 | 0.83 | GHSR (0.44) | KMT2AHDAC1MAPTSMN1; SMN2 | |
| SCHEMBL12515488 | 0.83 | TSHR (0.45) | TSHRKMT2ARAB9AKLKB1MMP2 | |
| SCHEMBL19486199 | 0.82 | TSHR (0.44) | TSHRKMT2AHDAC1KLKB1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2709619-B1 | COMPOUNDS FOR USE IN TREATMENT OF MUCOSITIS | CELLCEUTIX CORP (US) | 2017-10-11 | — | — | EP | disclosed |