Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.37 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.37 |
| ▸ | KCNB1 | Q14721 | 3/20 | 0.37 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | Q9HBH1 | 1/20 | 0.35 | |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19445611 | 0.94 | NPC1 (0.38) | KLKB1MMP2TSHRERAP2LNPEP | |
| SCHEMBL19445810 | 0.92 | KCNB1 (0.40) | KLKB1MMP2TSHRERAP2LNPEP | |
| SCHEMBL19445879 | 0.91 | KCNK3 (0.41) | KLKB1MMP2TSHRKCNB1HDAC1 | |
| SCHEMBL19445641 | 0.91 | ERAP2 (0.44) | KLKB1MMP2ERAP2LNPEPERAP1 | |
| SCHEMBL19445834 | 0.90 | MMP2 (0.39) | KLKB1MMP2TSHRKCNB1HDAC1 | |
| SCHEMBL12515368 | 0.89 | KLKB1 (0.41) | KLKB1MMP2TSHRERAP2LNPEP | |
| SCHEMBL19445616 | 0.89 | ALDH1A1 (0.40) | — | |
| SCHEMBL19445764 | 0.88 | KLKB1 (0.40) | KLKB1MMP2TSHRERAP2LNPEP | |
| SCHEMBL21371597 | 0.88 | KLKB1 (0.41) | KLKB1MMP2TSHRERAP2LNPEP | |
| SCHEMBL19445715 | 0.88 | KLKB1 (0.41) | KLKB1MMP2TSHRERAP2LNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2709619-B1 | COMPOUNDS FOR USE IN TREATMENT OF MUCOSITIS | CELLCEUTIX CORP (US) | 2017-10-11 | — | — | EP | disclosed |