Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | F11 | P03951 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19445763 | 0.85 | LMNA (0.40) | HSD17B10TSHRLMNASLC22A1ADRB2 | |
| SCHEMBL19445573 | 0.82 | LMNA (0.39) | HSD17B10TSHRLMNAKDM4EMEN1 | |
| SCHEMBL15317942 | 0.79 | LMNA (0.46) | HSD17B10TSHRLMNAAAK1KDM4E | |
| SCHEMBL19445591 | 0.78 | TSHR (0.39) | TSHRLMNAKDM4EMEN1KMT2A | |
| SCHEMBL13815091 | 0.77 | AAK1 (0.48) | AAK1 | |
| SCHEMBL7563176 | 0.77 | LMNA (0.61) | HSD17B10LMNASLC22A1ADRB2ADRB1 | |
| SCHEMBL13319568 | 0.76 | SUV39H2 (0.51) | AAK1 | |
| SCHEMBL130408 | 0.75 | ALDH1A1 (0.64) | LMNAKDM4EMEN1KMT2AMAPT | |
| SCHEMBL13973873 | 0.75 | LMNA (0.42) | HSD17B10LMNAKDM4EMEN1KMT2A | |
| SCHEMBL12444284 | 0.75 | ALDH1A1 (0.45) | HSD17B10LMNAKDM4EFAAHMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2709619-B1 | COMPOUNDS FOR USE IN TREATMENT OF MUCOSITIS | CELLCEUTIX CORP (US) | 2017-10-11 | — | — | EP | disclosed |