Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL756450 | 0.86 | MGLL (0.36) | KMT2AATMMGLL | |
| SCHEMBL20435281 | 0.81 | GLA (0.36) | — | |
| SCHEMBL15371562 | 0.78 | KMT2A (0.32) | KMT2AATMMGLL | |
| SCHEMBL26052513 | 0.76 | ALDH1A1 (0.33) | KMT2A | |
| SCHEMBL18685132 | 0.76 | — | — | |
| SCHEMBL19696388 | 0.74 | MGLL (0.30) | MGLL | |
| SCHEMBL18947917 | 0.73 | MGLL (0.31) | MGLL | |
| SCHEMBL17447 | 0.73 | MGLL (0.37) | MGLL | |
| SCHEMBL13258671 | 0.71 | — | — | |
| SCHEMBL9546488 | 0.70 | MGLL (0.33) | KMT2AATMMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170290827-A1 | INHIBITORS OF HEPATITIS C VIRUS | GILEAD PHARMASSET LLC | 2017-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170290827-A1 | INHIBITORS OF HEPATITIS C VIRUS | HAVCR2, SLC10A1, GOT1 | KMT2A 4606/4885ATM 4778/4885MGLL 279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.