Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19435511 | 0.81 | MAPT (0.62) | CYP11B1MAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL3111062 | 0.80 | MAPT (0.57) | MAPTALDH1A1KDM4EKMT2ANPC1 | |
| SCHEMBL17899915 | 0.80 | GPR84 (0.43) | CYP11B1MAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL17899838 | 0.80 | GPR84 (0.43) | CYP11B1MAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL23111255 | 0.78 | GPR84 (0.41) | CYP11B1MAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL17899914 | 0.77 | CCNC (0.43) | CYP11B1MAPTKDM4EKMT2ANPC1 | |
| SCHEMBL19435473 | 0.73 | CYP3A4 (0.63) | CYP11B1MAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL23989160 | 0.73 | CYP11B1 (0.50) | CYP11B1MAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL17899836 | 0.72 | SLC22A12 (0.55) | CYP11B1MAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL2812920 | 0.72 | CYP11B1 (0.66) | CYP11B1MAPTALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170290795-A1 | URAT1 INHIBITOR | J-PHARMA CO., LTD. (JP) | 2017-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170290795-A1 | URAT1 INHIBITOR | SLC10A1, XDH, URB2 | CYP11B1 785/4885MAPT 114/4885ALDH1A1 673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.