SCHEMBL17899836

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19435511	0.78	MAPT (0.62)	ALDH1A1KDM4EMEN1KMT2ACYP11B1
	SCHEMBL23111255	0.77	GPR84 (0.41)	ALDH1A1KDM4EHSD17B10CYP2C9CYP2C19
	SCHEMBL17899915	0.76	GPR84 (0.43)	ALDH1A1KDM4ECYP2C9GPR84MEN1
	SCHEMBL17899838	0.76	GPR84 (0.43)	ALDH1A1KDM4ECYP2C9GPR84MEN1
	SCHEMBL17899914	0.74	CCNC (0.43)	KDM4EGPR84MEN1KMT2ACYP11B1
	SCHEMBL30349528	0.73	SLC22A12 (0.43)	SLC22A12ALDH1A1KDM4EHSD17B10CYP2C9
	SCHEMBL31403193	0.73	CYP11B1 (0.51)	ALDH1A1KDM4EHSD17B10CYP2C9MEN1
	SCHEMBL19449093	0.72	CYP11B1 (0.43)	ALDH1A1KDM4ECYP2C9CYP2C19GPR84
	SCHEMBL5822854	0.72	ALDH1A1 (1.00)	SLC22A12ALDH1A1KDM4EHSD17B10CYP2C9
	SCHEMBL17899873	0.71	SLC22A12 (1.00)	SLC22A12ALDH1A1KDM4EHSD17B10CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.