Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTH | P32929 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.48 |
| ▸ | GRK2 | P25098 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19449709 | 0.81 | CTH (0.57) | CTHSMN1; SMN2MEN1KMT2AL3MBTL1 | |
| SCHEMBL13380947 | 0.81 | CTH (0.57) | CTHSMN1; SMN2MEN1KMT2AL3MBTL1 | |
| SCHEMBL16224322 | 0.79 | MEN1 (0.61) | SMN1; SMN2MEN1KMT2AL3MBTL1MAPT | |
| Hydrochloric Acid SCHEMBL17560849 | 0.79 | CTH (0.56) | CTHSMN1; SMN2MEN1KMT2AL3MBTL1 | |
| SCHEMBL4100494 | 0.78 | CTH (0.54) | CTHSMN1; SMN2MEN1KMT2AL3MBTL1 | |
| SCHEMBL4100496 | 0.78 | CTH (0.54) | CTHSMN1; SMN2MEN1KMT2AL3MBTL1 | |
| SCHEMBL9769014 | 0.76 | KMT2A (0.63) | CTHSMN1; SMN2MEN1KMT2AL3MBTL1 | |
| SCHEMBL9769012 | 0.76 | KMT2A (0.63) | CTHSMN1; SMN2MEN1KMT2AL3MBTL1 | |
| Water SCHEMBL9768838 | 0.74 | KMT2A (0.61) | CTHSMN1; SMN2MEN1KMT2AL3MBTL1 | |
| SCHEMBL433678 | 0.74 | KDM4E (0.75) | CTHCYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170291886-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2017-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170291886-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | DPM1, ABCB11, PIGS | CTH 1014/4885SMN1; SMN2 3002/4885MEN1 504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.