Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 12/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.40 |
| ▸ | LMNA | P02545 | 7/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 10/20 | 0.39 |
| ▸ | POLB | P06746 | 8/20 | 0.39 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21882648 | 0.92 | MEN1 (0.38) | MAPTKDM4ENPC1MEN1KMT2A | |
| SCHEMBL19449735 | 0.67 | GAA (0.58) | MAPTKDM4ENPC1MEN1KMT2A | |
| SCHEMBL17560799 | 0.65 | GAA (0.52) | MAPTKDM4ENPC1MEN1KMT2A | |
| SCHEMBL17560796 | 0.65 | GAA (0.52) | MAPTKDM4ENPC1MEN1KMT2A | |
| SCHEMBL19449748 | 0.64 | KMT2A (0.66) | MAPTKDM4ENPC1MEN1KMT2A | |
| SCHEMBL11961913 | 0.60 | GAA (0.79) | MAPTKDM4ENPC1MEN1KMT2A | |
| SCHEMBL1443318 | 0.60 | GAA (0.79) | MAPTKDM4ENPC1MEN1KMT2A | |
| SCHEMBL17897810 | 0.59 | ALDH1A1 (0.69) | MAPTKDM4ENPC1MEN1KMT2A | |
| SCHEMBL8848959 | 0.58 | NOX4 (0.76) | MAPTKDM4ENPC1MEN1KMT2A | |
| SCHEMBL8848964 | 0.58 | NOX4 (0.76) | MAPTKDM4ENPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170291886-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2017-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170291886-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | DPM1, ABCB11, PIGS | MAPT 3694/4885KDM4E 3521/4885NPC1 282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.