SCHEMBL194548

SCHEMBL194548

C=C(C)C(=O)NC(=O)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.52
KDM4E B2RXH2 3/20 0.52
GAA P10253 2/20 0.51
NPC1 O15118 3/20 0.50
RAB9A P51151 3/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
MAPT P10636 2/20 0.50
GLA P06280 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
HDAC3 O15379 1/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
IDO1 P14902 1/20 0.48
ALOX15 P16050 1/20 0.48
HDAC1 Q13547 1/20 0.48
CA9 Q16790 1/20 0.48
HDAC7 Q8WUI4 1/20 0.48
HDAC2 Q92769 1/20 0.48
HSD17B10 Q99714 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27773578 0.84 ALDH1A1 (0.52) ALDH1A1KDM4EGAANPC1RAB9A
SCHEMBL6551386 0.83 ALDH1A1 (0.55) ALDH1A1KDM4EGAANPC1RAB9A
SCHEMBL28362828 0.83 ALDH1A1 (0.61) ALDH1A1KDM4EGAANPC1RAB9A
SCHEMBL194581 0.82 ALDH1A1 (0.55) ALDH1A1GAANPC1RAB9AMEN1
SCHEMBL10408109 0.82 CES2 (0.52) ALDH1A1KDM4EMAPTL3MBTL1TDP1
SCHEMBL23258930 0.81 TPMT (0.42) ALDH1A1KDM4EMEN1KMT2AMAPT
SCHEMBL195428 0.81 ALDH1A1 (0.50) ALDH1A1KDM4ENPC1RAB9AMEN1
SCHEMBL28815026 0.80 ALDH1A1 (0.50) ALDH1A1KDM4EGAANPC1RAB9A
SCHEMBL29324398 0.80 ALDH1A1 (0.50) ALDH1A1KDM4EGAANPC1RAB9A
SCHEMBL20100374 0.79 HDAC1 (0.56) ALDH1A1NPC1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 230 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010869-A Dioxygen di-oxygen benzothiazepines Synthesis method of heptanone derivative 新疆大学 2026-05-12 CN disclosed
CN-122010870-A Ester group substitution dibenzothio of (C) Synthesis method of azepine derivative 新疆大学 2026-05-12 CN disclosed
CN-118930483-A Synthesis method of isoquinolone selenocyanate 新疆大学 2024-11-12 CN disclosed
CN-118530176-A Synthesis method of ester-substituted isoquinoline diketone and 3, 3-disubstituted indole oxide 新疆大学 2024-08-23 CN disclosed
CN-114832862-B Catalytic composition for coupling reaction and application of catalytic composition in preparation of isoquinoline-1, 3-dione compounds 中国药科大学 2023-06-30 CN disclosed
US-11209734-B2 Oxime ester photoinitiators BASF SE 2021-12-28 US disclosed
US-11209733-B2 Oxime ester photoinitiators BASF SE 2021-12-28 US disclosed
US-11204554-B2 Oxime ester photoinitiators BASF SE 2021-12-21 US disclosed
CN-107652222-B Oxime ester photoinitiators 巴斯夫欧洲公司 2021-09-10 CN disclosed
EP-3019473-B1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2020-02-19 EP disclosed
US-6596445-B1 Initiators for photopolymerization of radically polymerizable compounds CIBA SPECIALTY CHEMICALS CORPORATION 2003-07-22 US disclosed
WO-2003010602-A1 PHOTOSENSITIVE RESIN COMPOSITION CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-02-06 WO disclosed
WO-2002100903-A1 OXIME ESTER PHOTOINITIATORS HAVING A COMBINED STRUCTURE CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-12-19 WO disclosed
US-20020188084-A1 Stimuli-responsive polymer utilizing keto-enol tautomerization and stimuli-responsive separating material and chemical-releasing capsule comprising the same JNC CORPORATION (JP) 2002-12-12 US disclosed
US-20020020832-A1 Photosensitive resin composition CIBA SPECIALTY CHEMICALS CORP. 2002-02-21 US disclosed
US-20010012596-A1 For resist applications; thermostability, storage stability CIBA SPECIALTY CHEMICALS CORP. 2001-08-09 US disclosed
CN-1299812-A Oximate light initiator CIBA SC HOLDING AG (CH) 2001-06-20 CN disclosed
CN-1241562-A New O-acyloxime photointiators CIBA SPECIALY CHEMICALS HOLDIN (CH) 2000-01-19 CN disclosed
EP-0922715-A2 Stimuli-responsive polymer utilizing keto-enol tautomerization AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY MITI (JP) 1999-06-16 EP disclosed
US-5663212-A Light-sensitive resin composition FUJI PHOTO FILM CO., LTD. (JP) 1997-09-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11209734-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 ALDH1A1 823/4885KDM4E 1549/4885GAA 4457/4885
US-11204554-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 ALDH1A1 779/4885KDM4E 1583/4885GAA 4437/4885
US-11209733-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 ALDH1A1 823/4885KDM4E 1549/4885GAA 4457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.