SCHEMBL195428

SCHEMBL195428

C=C(C)C(=O)NC(=O)c1ccc(Cl)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
LMNA P02545 4/20 0.50
MAPT P10636 3/20 0.50
KDM4E B2RXH2 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
ALOX12 P18054 2/20 0.47
HTT P42858 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
POLB P06746 4/20 0.47
NPC1 O15118 3/20 0.46
RAB9A P51151 2/20 0.46
KCNH2 Q12809 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
PTGS2 P35354 1/20 0.46
KMT2A Q03164 4/20 0.46
MEN1 O00255 2/20 0.46
EPHX1 P07099 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24554797 0.85 ALDH1A1 (0.53) ALDH1A1LMNAMAPTKDM4EL3MBTL1
SCHEMBL194581 0.83 ALDH1A1 (0.55) ALDH1A1LMNAMAPTALOX12HTT
SCHEMBL23258930 0.81 TPMT (0.42) ALDH1A1MAPTKDM4EHTTSMN1; SMN2
SCHEMBL194548 0.81 ALDH1A1 (0.52) ALDH1A1MAPTKDM4EL3MBTL1ALOX12
SCHEMBL13273458 0.80 ALDH1A1 (0.57) ALDH1A1LMNAMAPTKDM4EL3MBTL1
SCHEMBL20100374 0.80 HDAC1 (0.56) ALDH1A1LMNAMAPTHTTSMN1; SMN2
SCHEMBL15047786 0.80 MAPT (0.67) ALDH1A1LMNAMAPTKDM4EL3MBTL1
SCHEMBL16661813 0.79 PLK1 (0.62) ALDH1A1LMNAMAPTHTTSMN1; SMN2
SCHEMBL20100408 0.79 NPC1 (0.50) NPC1RAB9A
SCHEMBL28959072 0.79 CES2 (0.60) ALDH1A1LMNAMAPTKDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 877 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109791361-B Positive lithographic printing plate precursor, method for producing same, and method for producing lithographic printing plate 富士胶片株式会社 2022-06-03 CN disclosed
US-11209733-B2 Oxime ester photoinitiators BASF SE 2021-12-28 US disclosed
US-11209734-B2 Oxime ester photoinitiators BASF SE 2021-12-28 US disclosed
US-11204554-B2 Oxime ester photoinitiators BASF SE 2021-12-21 US disclosed
EP-3521927-B1 POSITIVE WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD FOR MANUFACTURING THE PRECURSOR AND METHOD FOR PRODUCING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORP (JP) 2021-10-27 EP disclosed
CN-107652222-B Oxime ester photoinitiators 巴斯夫欧洲公司 2021-09-10 CN disclosed
US-20210197516-A1 LAMINATE FUJIFILM CORPORATION (JP) 2021-07-01 US disclosed
CN-111295291-B Security element and security system 富士胶片株式会社 2021-05-07 CN disclosed
EP-3124548-B1 MICROLENS COMPRING A TRANSPARENT FILM AND SOLID-STATE IMAGING DEVICE USING THE SAME FUJIFILM CORP (JP) 2020-12-02 EP disclosed
US-20200316914-A1 LAMINATE, COMPOSITE, AND METHOD FOR PRODUCING COMPOSITE FUJIFILM CORPORATION (JP) 2020-10-08 US disclosed
EP-0617332-A1 Manufacturing process for a lead-frame forming material FUJI PHOTO FILM CO., LTD. (JP) 1994-09-28 EP disclosed
EP-0399755-B1 Light-sensitive composition and presensitized plate for use in making lithographic printing plates FUJI PHOTO FILM CO LTD (JP) 1994-03-30 EP disclosed
EP-0579237-A2 PS plate and method for processing same FUJI PHOTO FILM CO., LTD. (JP) 1994-01-19 EP disclosed
US-5250393-A Containing diazo resin and alkali metal or ammonium silicate FUJI PHOTO FILM CO., LTD. (JP) 1993-10-05 US disclosed
EP-0530815-A1 Presensitized plate for use in making lithographic printing plate Fuji Photo Film Co., Ltd. (JP) 1993-03-10 EP disclosed
EP-0492959-A1 Method for developing presensitized plate for use in making lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1992-07-01 EP disclosed
EP-0487343-A1 Process for preparing a lithographic plate Fuji Photo Film Co., Ltd. (JP) 1992-05-27 EP disclosed
US-5112743-A Aromatic-aldehyde diazo resins FUJI PHOTO FILM CO., LTD. (JP) 1992-05-12 US disclosed
EP-0415422-A2 Method for forming images FUJI PHOTO FILM CO., LTD. (JP) 1991-03-06 EP disclosed
EP-0399755-A1 Light-sensitive composition and presensitized plate for use in making lithographic printing plates Fuji Photo Film Co., Ltd. (JP) 1990-11-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11209734-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 ALDH1A1 823/4885LMNA 2575/4885MAPT 4436/4885
US-11204554-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 ALDH1A1 779/4885LMNA 2745/4885MAPT 4479/4885
US-11209733-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 ALDH1A1 823/4885LMNA 2575/4885MAPT 4436/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.