Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19458015 | 0.81 | — | — | |
| SCHEMBL4854325 | 0.78 | ALDH1A1 (0.45) | ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL4316110 | 0.73 | ALDH1A1 (0.53) | ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL214755 | 0.73 | ALDH1A1 (0.53) | ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL150680 | 0.71 | ALDH1A1 (0.50) | ALDH1A1TSHRHSD17B10TDP1 | |
| Methyl Alcohol SCHEMBL9630414 | 0.71 | ALDH1A1 (0.50) | ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL968944 | 0.71 | ALDH1A1 (0.50) | ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL21831923 | 0.71 | ALDH1A1 (0.50) | ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL9866292 | 0.69 | — | — | |
| SCHEMBL1331774 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3231795-B1 | METHOD FOR PREPARING 2,5-DISUBSTITUTED FURAN COMPOUND | NINGBO INST MATERIALS TECH & ENG CAS (CN) | 2021-09-15 | — | — | EP | claimed |
| CN-112409305-A | Preparation method of 2, 5-diacyl furan compound | 中国科学院宁波材料技术与工程研究所 | 2021-02-26 | — | — | CN | claimed |
| US-10125110-B2 | Method for preparing 2,5-disubstituted furan compound | NINGBO INSTITUTE OF MATERIALS TECHNOLOGY & ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) | 2018-11-13 | — | — | US | claimed |
| US-20170320844-A1 | METHOD FOR PREPARING 2,5-DISUBSTITUTED FURAN COMPOUND | NINGBO INSTITUTE OF MATERIALS TECHNOLOGY & ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) | 2017-11-09 | — | — | US | claimed |
| CN-112409305-A | Preparation method of 2, 5-diacyl furan compound | 中国科学院宁波材料技术与工程研究所 | 2021-02-26 | — | — | CN | disclosed |
| US-10125110-B2 | Method for preparing 2,5-disubstituted furan compound | NINGBO INSTITUTE OF MATERIALS TECHNOLOGY & ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) | 2018-11-13 | — | — | US | disclosed |
| US-20170320844-A1 | METHOD FOR PREPARING 2,5-DISUBSTITUTED FURAN COMPOUND | NINGBO INSTITUTE OF MATERIALS TECHNOLOGY & ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) | 2017-11-09 | — | — | US | disclosed |
| EP-3231795-A1 | METHOD FOR PREPARING 2,5-DISUBSTITUTED FURAN COMPOUND | Ningbo Institute Of Material Technology And Engineering Chinese Academy of Sciences (CN) | 2017-10-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170320844-A1 | METHOD FOR PREPARING 2,5-DISUBSTITUTED FURAN COMPOUND | ALOX5, PFAS, APEH | ALDH1A1 561/4885TSHR 4544/4885HSD17B10 804/4885 |
| US-10125110-B2 | Method for preparing 2,5-disubstituted furan compound | ALOX5, PFAS, APEH | ALDH1A1 561/4885TSHR 4544/4885HSD17B10 804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.