SCHEMBL214755

SCHEMBL214755

CC(=O)OC(=O)C(C)(C)C

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.53
TSHR P16473 2/20 0.53
HSD17B10 Q99714 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
ELANE P08246 8/20 0.36
GAA P10253 1/20 0.35
PRKCA P17252 1/20 0.32
LMNA P02545 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4316110 1.00 ALDH1A1 (0.53) ALDH1A1TSHRHSD17B10TDP1ELANE
Methyl Alcohol SCHEMBL9630414 0.97 ALDH1A1 (0.50) ALDH1A1TSHRHSD17B10TDP1ELANE
SCHEMBL21831923 0.97 ALDH1A1 (0.50) ALDH1A1TSHRHSD17B10TDP1ELANE
SCHEMBL5780612 0.86 ALDH1A1 (0.45) ALDH1A1TSHRHSD17B10TDP1ELANE
SCHEMBL65267 0.83 ELANE (0.40) ALDH1A1TSHRELANEPRKCA
Ammonia Solution, Strong SCHEMBL25421893 0.80 ELANE (0.39) ALDH1A1TSHRELANEPRKCA
SCHEMBL7026388 0.80 ELANE (0.39) ALDH1A1TSHRELANEPRKCA
SCHEMBL3204404 0.80 ALDH1A1 (0.39) ALDH1A1TSHRHSD17B10TDP1ELANE
SCHEMBL6921707 0.79 ALDH1A1 (0.35) ALDH1A1TSHRELANEPRKCA
SCHEMBL22362392 0.78 ELANE (0.37) ALDH1A1TSHRELANEPRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1393 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12612382-B2 Process for preparing 6-substituted-1-(2H)-isoquinolinones and intermediate compound VALO HEALTH INC. (US) 2026-04-28 US claimed
CN-121574269-A Starch modification hydrolysis method 上海建工建材科技集团股份有限公司 2026-02-27 CN claimed
US-20250296923-A1 PROCESS FOR PREPARING 6-SUBSTITUTED-1-(2H)-ISOQUINOLINONES AND INTERMEDIATE COMPOUND VALO HEALTH, INC. (US) 2025-09-25 US claimed
CN-119751333-A Preparation method of N-alkyl-4-nitrophthalimide 广东优巨先进新材料股份有限公司 2025-04-04 CN claimed
CN-119684399-A Synthesis method of Val-Cit dipeptide linker 浙江工业大学 2025-03-25 CN claimed
CN-119630643-A Process and intermediate compounds for the preparation of 6-substituted-1- (2H) -isoquinolinones 瓦洛健康公司 2025-03-14 CN claimed
US-20240287031-A1 PROCESS FOR PREPARING 6-SUBSTITUTED-1-(2H)-ISOQUINOLINONES AND INTERMEDIATE COMPOUND VALO HEALTH, INC. (US) 2024-08-29 US claimed
US-20240287030-A1 PROCESS FOR PREPARING 6-SUBSTITUTED-1-(2H)-ISOQUINOLINONES AND INTERMEDIATE COMPOUND VALO HEALTH, INC. (US) 2024-08-29 US claimed
EP-4402129-A1 <SMALLCAPS/>? ? ?H? ? ? ? ?PROCESS FOR PREPARING 6-SUBSTITUTED-1-(2)-ISOQUINOLINONES AND INTERMEDIATE COMPOUND Valo Health, Inc. (US) 2024-07-24 EP claimed
WO-2024094637-A1 PROCESS FOR THE PREPARATION OF CYCLIC KETONES ARXADA AG (CH) 2024-05-10 WO claimed
EP-0219196-B1 SURFACE TREATMENT OF SOFT CONTACT LENSES Sola U.S.A. Inc. (US) 1990-05-09 EP claimed
EP-0239194-A2 Methods for preparing hydroxy compounds and intermediates SYMBICOM AB (SE) 1987-09-30 EP claimed
US-4687816-A USING ORGANIC ACID ANHYDRIDE SOLA U.S.A. INC. (US) 1987-08-18 US claimed
US-4666249-A Surface-treated contact lens and method of producing SOLA U.S.A. INC. (US) 1987-05-19 US claimed
EP-0219196-A1 Surface treatment of soft contact lenses Sola U.S.A. Inc. (US) 1987-04-22 EP claimed
EP-0157088-B1 PROCESS FOR THE PREPARATION OF POLYISOCYANATES HAVING A BIURET STRUCTURE BAYER AG (DE) 1987-01-14 EP claimed
US-4625052-A REACTING DIISOCYANATES WITH WATER IN PRESENCE OF TRI-SUBSTITUTED ACETIC ACIDS ANDOR ANHYDRIDES BAYER AKTIENGESELLSCHAFT (DE) 1986-11-25 US claimed
US-4603013-A Estrane derivatives SCHERING AKTIENGESELLSCHAFT (DE) 1986-07-29 US claimed
EP-0051143-B1 PROCESS FOR THE PREPARATION OF 3-BETA, 7-BETA-DIHYDROXY-DELTA-5 STEROIDS SCHERING AKTIENGESELLSCHAFT (DE) 1984-07-04 EP claimed
US-4416985-A Process for preparing 3β,7β-dihydroxy-Δ5 -steroids SCHERING, AKTIENGESELLSCHAFT (DE) 1983-11-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240287031-A1 PROCESS FOR PREPARING 6-SUBSTITUTED-1-(2H)-ISOQUINOLINONES AND INTERMEDIATE COMPOUND ROCK1, ROCK2, CIT ALDH1A1 1653/4885TSHR 4618/4885HSD17B10 1796/4885
US-20250296923-A1 PROCESS FOR PREPARING 6-SUBSTITUTED-1-(2H)-ISOQUINOLINONES AND INTERMEDIATE COMPOUND ROCK1, ROCK2, CIT ALDH1A1 1653/4885TSHR 4618/4885HSD17B10 1796/4885
US-12612382-B2 Process for preparing 6-substituted-1-(2H)-isoquinolinones and intermediate compound ROCK1, RHOA, ABL1 ALDH1A1 3101/4885TSHR 506/4885HSD17B10 3552/4885
US-20240287030-A1 PROCESS FOR PREPARING 6-SUBSTITUTED-1-(2H)-ISOQUINOLINONES AND INTERMEDIATE COMPOUND ROCK1, ROCK2, CIT ALDH1A1 1653/4885TSHR 4618/4885HSD17B10 1796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.