Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16522849 | 0.74 | KDM4E (0.40) | MAPTPKMHSD17B10TDP1LMNA | |
| SCHEMBL12431217 | 0.72 | KMT2A (0.60) | MAPTPKMHSD17B10TDP1MEN1 | |
| SCHEMBL1355720 | 0.69 | MAPT (0.39) | MAPTPKMHSD17B10TDP1MEN1 | |
| SCHEMBL31186169 | 0.69 | PDPK1 (0.70) | PDPK1TDP1LMNAMEN1KMT2A | |
| SCHEMBL8171942 | 0.67 | CA1 (0.57) | PDPK1MAPTMEN1KMT2ACA2 | |
| SCHEMBL19829835 | 0.67 | PDPK1 (0.53) | PDPK1KMT2ACA2PDK1 | |
| SCHEMBL10161062 | 0.67 | TDP1 (0.45) | HSD17B10TDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL21729382 | 0.66 | KDM4E (0.34) | TDP1MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL8385131 | 0.66 | ALDH1A1 (0.57) | PDPK1MAPTTDP1LMNACYP2C19 | |
| SCHEMBL11904537 | 0.65 | TDP1 (0.61) | HSD17B10TDP1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3231795-B1 | METHOD FOR PREPARING 2,5-DISUBSTITUTED FURAN COMPOUND | NINGBO INST MATERIALS TECH & ENG CAS (CN) | 2021-09-15 | — | — | EP | disclosed |
| CN-112409305-A | Preparation method of 2, 5-diacyl furan compound | 中国科学院宁波材料技术与工程研究所 | 2021-02-26 | — | — | CN | disclosed |
| US-10125110-B2 | Method for preparing 2,5-disubstituted furan compound | NINGBO INSTITUTE OF MATERIALS TECHNOLOGY & ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) | 2018-11-13 | — | — | US | disclosed |
| US-20170320844-A1 | METHOD FOR PREPARING 2,5-DISUBSTITUTED FURAN COMPOUND | NINGBO INSTITUTE OF MATERIALS TECHNOLOGY & ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) | 2017-11-09 | — | — | US | disclosed |
| EP-3231795-A1 | METHOD FOR PREPARING 2,5-DISUBSTITUTED FURAN COMPOUND | Ningbo Institute Of Material Technology And Engineering Chinese Academy of Sciences (CN) | 2017-10-18 | — | — | EP | disclosed |
| CN-105732546-A | Preparation method of 2, 5-diacyl furan compound | 中国科学院宁波材料技术与工程研究所 | 2016-07-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170320844-A1 | METHOD FOR PREPARING 2,5-DISUBSTITUTED FURAN COMPOUND | ALOX5, PFAS, APEH | PDPK1 3843/4885MAPT 4456/4885PKM 3126/4885 |
| US-10125110-B2 | Method for preparing 2,5-disubstituted furan compound | ALOX5, PFAS, APEH | PDPK1 3843/4885MAPT 4456/4885PKM 3126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.