SCHEMBL1355720

SCHEMBL1355720

O=C(Cl)c1ccc(C(=O)Cl)o1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.39
PKM P14618 1/20 0.39
HSD17B10 Q99714 1/20 0.39
ALDH1A1 P00352 5/20 0.36
TDP1 Q9NUW8 1/20 0.36
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ALOX15 P16050 1/20 0.33
HPGD P15428 1/20 0.32
KLK7 P49862 1/20 0.32
HTT P42858 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
DAO P14920 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3063658 0.87 KMT2A (0.38) MAPTPKMHSD17B10ALDH1A1MEN1
SCHEMBL31462930 0.86 ALDH1A1 (0.42) HSD17B10ALDH1A1TDP1MEN1KMT2A
SCHEMBL11274940 0.84
SCHEMBL301866 0.82
SCHEMBL972027 0.82
SCHEMBL353183 0.82
SCHEMBL13180448 0.78
SCHEMBL2915232 0.78 CHRNA4 (0.47) ALDH1A1CES1
SCHEMBL3384529 0.78 ALDH1A1 (0.45) MAPTALDH1A1TDP1HPGDHTT
SCHEMBL3058890 0.78 TDP1 (0.45) MAPTHSD17B10ALDH1A1TDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 441 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250332075-A1 POLYAMIDE MICROCAPSULES FIRMENICH & CIE (CH) 2025-10-30 US claimed
US-20250312763-A1 POLYAMIDE MICROCAPSULES FIRMENICH SA (CH) 2025-10-09 US claimed
CN-120149740-A Flame-retardant bio-based lithium battery diaphragm and production process thereof 合肥卓宸新材料科技有限公司 2025-06-13 CN claimed
CN-120118306-A Modified furyl polyamide and preparation method thereof 安徽利科新材料科技有限公司 2025-06-10 CN claimed
CN-116082634-B Sulfonic acid group modified furyl polyamide and preparation method and device thereof 安徽利科新材料科技有限公司 2025-05-23 CN claimed
WO-2025101819-A1 ENTRAPPED SMALL AMINES IN NANOPOROUS MATERIALS FOR GAS CAPTURE THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2025-05-15 WO claimed
CN-119971800-A High-stability anti-pollution efficient composite reverse osmosis membrane and preparation method thereof 中国矿业大学(北京) 2025-05-13 CN claimed
CN-119944228-A Bio-based aromatic polyamide lithium battery diaphragm and preparation method thereof 合肥卓宸新材料科技有限公司 2025-05-06 CN claimed
CN-119841793-A 2, 5-Bis (4-fluorobenzoyl) furan and preparation method thereof 合肥利夫生物科技有限公司 2025-04-18 CN claimed
WO-2025066071-A1 SEMI-BIO-BASED POLYAMIDE CONTAINING CROSS-LINKED STRUCTURE, PREPARATION METHOD THEREFOR AND USE THEREOF 安徽利科新材料科技有限公司 2025-04-03 WO claimed
WO-2015014465-A1 NOVEL STERICALLY HINDERED CYCLIC AMINES CLARIANT INTERNATIONAL LTD (CH) 2015-02-05 WO claimed
EP-2470517-B1 2,5-FURAN DICARBOXYLATES COMPRISING ISODECANOLS, AND USE THEREOF EVONIK DEGUSSA GMBH (DE) 2014-04-16 EP claimed
EP-2470518-B1 2,5-FURAN DICARBOXYLATE DERIVATIVES, AND USE THEREOF AS PLASTICIZERS EVONIK DEGUSSA GMBH (DE) 2014-04-16 EP claimed
US-20120220507-A1 2,5-FURAN DICARBOXYLATE DERIVATIVES, AND USE THEREOF AS PLASTICIZERS EVONIK OXENO GMBH (DE) 2012-08-30 US claimed
US-20120202725-A1 2,5-FURAN DICARBOXYLATES COMPRISING ISODECANOLS, AND USE THEREOF EVONIK OXENO GMBH (DE) 2012-08-09 US claimed
US-20100280186-A1 FURANIC-MODIFIED AMINE-BASED CURATIVES BATTELLE MEMORIAL INSTITUTE 2010-11-04 US claimed
US-20090018264-A1 RESIN COMPOSITION CANON KABUSHIKI KAISHA (JP) 2009-01-15 US claimed
US-20080207847-A1 Furanic-modified amine-based curatives BATTELLE MEMORIAL INSTITUTE 2008-08-28 US claimed
EP-0539870-B1 Hydrophilic asymmetric chemically resistant polyaramide membranes HOECHST AG (DE) 1996-08-28 EP claimed
US-5536408-A ULTRAFILTRATION, BIOCHEMISTRY SUPPORTS HOECHST AKTIENGESELLSCHAFT (DE) 1996-07-16 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120220507-A1 2,5-FURAN DICARBOXYLATE DERIVATIVES, AND USE THEREOF AS PLASTICIZERS OGDH, SDHA, SLC16A7 MAPT 2829/4885PKM 862/4885HSD17B10 88/4885
US-20100280186-A1 FURANIC-MODIFIED AMINE-BASED CURATIVES UMPS, SRM, PAM MAPT 2353/4885PKM 545/4885HSD17B10 2754/4885
US-20250332075-A1 POLYAMIDE MICROCAPSULES PSAP, POLI, PGA5 MAPT 1026/4885PKM 2319/4885HSD17B10 3438/4885
US-20250312763-A1 POLYAMIDE MICROCAPSULES PSAP, PPHLN1, PARG MAPT 1421/4885PKM 1520/4885HSD17B10 3609/4885
US-20080207847-A1 Furanic-modified amine-based curatives DDC, AOC1, ESD MAPT 2609/4885PKM 2487/4885HSD17B10 1560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.