Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 3/20 | 0.35 |
| ▸ | ACACA | Q13085 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | VDR | P11473 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16361931 | 0.95 | ALDH1A1 (0.38) | MAPTNPSR1ALDH1A1MAPK1TSHR | |
| SCHEMBL16864161 | 0.93 | TAS1R3 (0.35) | MAPTNPSR1ACACBACACAALDH1A1 | |
| SCHEMBL17130508 | 0.91 | TAS1R3 (0.42) | MAPTALDH1A1TAS1R3TAS1R1TP53 | |
| SCHEMBL19139144 | 0.90 | TAS1R3 (0.33) | ALDH1A1TAS1R3TAS1R1VDRTP53 | |
| SCHEMBL13191290 | 0.90 | TAS1R3 (0.33) | MAPTALDH1A1TAS1R3TAS1R1VDR | |
| SCHEMBL15499183 | 0.89 | TAS1R3 (0.33) | ALDH1A1TAS1R3TAS1R1VDRTP53 | |
| SCHEMBL13063363 | 0.87 | TAS1R3 (0.35) | MAPTNPSR1ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL13660382 | 0.87 | ELANE (0.33) | ALDH1A1TAS1R3TAS1R1VDRTP53 | |
| SCHEMBL12942547 | 0.85 | VDR (0.32) | TAS1R3TAS1R1VDRTP53GAA | |
| SCHEMBL12942432 | 0.83 | ALDH1A1 (0.38) | MAPTNPSR1ALDH1A1MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9791791-B2 | Electrophotographic photoreceptor, electrophotographic cartridge, image forming apparatus, and charge transport substance | MITSUBISHI CHEMICAL CORPORATION (JP) | 2017-10-17 | — | — | US | disclosed |