Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.50 |
| ▸ | CA6 | P23280 | 4/20 | 0.50 |
| ▸ | CA7 | P43166 | 4/20 | 0.50 |
| ▸ | CA9 | Q16790 | 4/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA4 | P22748 | 3/20 | 0.50 |
| ▸ | CA5A | P35218 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CASP2 | P42575 | 2/20 | 0.50 |
| ▸ | F13A1 | P00488 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | THPO | P40225 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21799969 | 0.96 | CA12 (0.48) | CA12CA6CA7CA9CA14 | |
| SCHEMBL23468508 | 0.91 | CA12 (0.48) | CA12CA6CA7CA9CA14 | |
| SCHEMBL21799824 | 0.89 | CA12 (0.50) | CA12CA6CA7CA9CA14 | |
| SCHEMBL10045097 | 0.89 | ALDH1A1 (0.48) | CA12CA6CA7CA9CA14 | |
| SCHEMBL21799740 | 0.87 | TSHR (0.48) | CA12CA6CA7CA9CA14 | |
| SCHEMBL21799671 | 0.87 | TSHR (0.48) | CA12CA6CA7CA9CA14 | |
| SCHEMBL21799731 | 0.87 | TSHR (0.48) | CA12CA6CA7CA9CA14 | |
| SCHEMBL21799895 | 0.87 | TSHR (0.48) | CA12CA6CA7CA9CA14 | |
| SCHEMBL21799521 | 0.87 | TSHR (0.48) | CA12CA6CA7CA9CA14 | |
| SCHEMBL21799641 | 0.87 | TSHR (0.48) | CA12CA6CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3606344-B1 | COMPOSITIONS AND METHODS COMPRISING A TRIARYL POLYAMINE | CURZA GLOBAL LLC (US) | 2022-08-17 | — | — | EP | disclosed |
| US-11352315-B2 | Compositions and methods comprising a triaryl polyamine | CURZA GLOBAL, LLC (US) | 2022-06-07 | — | — | US | disclosed |
| CN-110785082-B | Compositions and methods comprising triarylpolyamines | 库扎环球有限责任公司 | 2021-12-28 | — | — | CN | disclosed |
| CN-110785082-A | Compositions and methods comprising triarylpolyamines | 库扎环球有限责任公司 | 2020-02-11 | — | — | CN | disclosed |
| US-20200031757-A1 | COMPOSITIONS AND METHODS COMPRISING A TRIARYL POLYAMINE | CURZA GLOBAL, LLC (US) | 2020-01-30 | — | — | US | disclosed |
| US-20170298002-A1 | METHOD OF PRODUCING N-ALKYL POLYAMINES | CURZA GLOBAL, LLC | 2017-10-19 | — | — | US | disclosed |
| US-20170298002-A1 | METHOD OF PRODUCING N-ALKYL POLYAMINES | CURZA GLOBAL, LLC | 2017-10-19 | — | — | US | disclosed |
| US-20170298002-A1 | METHOD OF PRODUCING N-ALKYL POLYAMINES | CURZA GLOBAL, LLC | 2017-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11352315-B2 | Compositions and methods comprising a triaryl polyamine | SRM, PARG, PARN | CA12 4744/4885CA6 4331/4885CA7 3797/4885 |
| US-20200031757-A1 | COMPOSITIONS AND METHODS COMPRISING A TRIARYL POLYAMINE | SRM, PARG, PARN | CA12 4744/4885CA6 4331/4885CA7 3797/4885 |
| US-20170298002-A1 | METHOD OF PRODUCING N-ALKYL POLYAMINES | SRM, PNMT, SMS | CA12 2715/4885CA6 1846/4885CA7 2566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.