Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | PRKCA | P17252 | 5/20 | 0.48 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.48 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.48 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | DGKA | P23743 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8502959 | 1.00 | MAPT (0.54) | MAPTMAPK1LMNAPRKCAPRKCE | |
| SCHEMBL769533 | 1.00 | MAPT (0.54) | MAPTMAPK1LMNAPRKCAPRKCE | |
| SCHEMBL2800456 | 1.00 | MAPT (0.54) | MAPTMAPK1LMNAPRKCAPRKCE | |
| SCHEMBL373408 | 1.00 | MAPT (0.54) | MAPTMAPK1LMNAPRKCAPRKCE | |
| SCHEMBL8190440 | 1.00 | MAPT (0.54) | MAPTMAPK1LMNAPRKCAPRKCE | |
| SCHEMBL15262436 | 1.00 | MAPT (0.54) | MAPTMAPK1LMNAPRKCAPRKCE | |
| SCHEMBL15463455 | 1.00 | MAPT (0.54) | MAPTMAPK1LMNAPRKCAPRKCE | |
| SCHEMBL11801281 | 1.00 | MAPT (0.54) | MAPTMAPK1LMNAPRKCAPRKCE | |
| SCHEMBL6357113 | 1.00 | MAPT (0.54) | MAPTMAPK1LMNAPRKCAPRKCE | |
| SCHEMBL10763839 | 1.00 | MAPT (0.54) | MAPTMAPK1LMNAPRKCAPRKCE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11007161-B1 | Ibuprofen nanoparticle carriers encapsulated with hermatic surfactant films | MORRISON Eric (US) | 2021-05-18 | — | — | US | disclosed |
| US-10596117-B1 | Lipoleosomes as carriers for aromatic amide anesthetic compounds | MORRISON Eric (US) | 2020-03-24 | — | — | US | disclosed |
| US-10561627-B2 | Ibuprofen nanoparticle carriers encapsulated with hermetic surfactant films | MORRISON Eric (US) | 2020-02-18 | — | — | US | disclosed |
| US-20170296496-A1 | Ibuprofen Nanoparticle Carriers Encapsulated with Hermatic Surfactant Films | MORRISON Eric (US) | 2017-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10561627-B2 | Ibuprofen nanoparticle carriers encapsulated with hermetic surfactant films | S100B, HMOX2, HSPA1B | MAPT 2584/4885MAPK1 4104/4885LMNA 2582/4885 |
| US-20170296496-A1 | Ibuprofen Nanoparticle Carriers Encapsulated with Hermatic Surfactant Films | LIPA, HMOX2, S100B | MAPT 2693/4885MAPK1 4293/4885LMNA 2129/4885 |
| US-11007161-B1 | Ibuprofen nanoparticle carriers encapsulated with hermatic surfactant films | AHR, ARNT, SULT2A1 | MAPT 878/4885MAPK1 4490/4885LMNA 2834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.