Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Hydrocortisone Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 known ✓ | P04150 | 9/20 | 0.74 |
| ▸ | HIF1A | Q16665 | 10/20 | 0.77 |
| ▸ | PGR | P06401 | 2/20 | 0.77 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.77 |
| ▸ | LMNA | P02545 | 2/20 | 0.77 |
| ▸ | AR | P10275 | 1/20 | 0.77 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.74 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.74 |
| ▸ | MAPT | P10636 | 2/20 | 0.74 |
| ▸ | SHBG | P04278 | 1/20 | 0.74 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.74 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrocortisone Phosphoric Acid SCHEMBL1761098 | 1.00 | HIF1A (0.77) | HIF1APGRSERPINA6LMNAAR | |
| Hydrocortisone Phosphoric Acid SCHEMBL42271 | 1.00 | HIF1A (0.77) | HIF1APGRSERPINA6LMNAAR | |
| Hydrocortisone Phosphoric Acid SCHEMBL21647387 | 0.99 | HIF1A (0.75) | HIF1APGRSERPINA6LMNAAR | |
| Hydrocortisone Phosphoric Acid SCHEMBL21313286 | 0.97 | HIF1A (0.81) | HIF1APGRSERPINA6LMNAAR | |
| Hydrocortisone Phosphoric Acid SCHEMBL6122495 | 0.95 | HIF1A (0.86) | HIF1APGRSERPINA6LMNAAR | |
| Hydrocortisone Phosphoric Acid SCHEMBL28230177 | 0.94 | HIF1A (0.69) | HIF1APGRSERPINA6LMNAAR | |
| Hydrocortisone Phosphoric Acid SCHEMBL22982268 | 0.93 | HIF1A (0.77) | HIF1APGRSERPINA6LMNAAR | |
| Hydrocortisone Phosphoric Acid SCHEMBL13026155 | 0.92 | HIF1A (0.78) | HIF1APGRSERPINA6LMNAAR | |
| Hydrocortisone Phosphoric Acid SCHEMBL7868481 | 0.92 | HIF1A (0.78) | HIF1APGRSERPINA6LMNAAR | |
| Hydrocortisone Phosphoric Acid SCHEMBL250125 | 0.92 | HIF1A (0.78) | HIF1APGRSERPINA6LMNAAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3442587-B1 | MULTI-DOSE COMPOSITIONS CONTAINING AN ANTIMICROBIAL POLYAMIDE OR OCTENIDINE PRESERVATIVE | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-08-18 | — | — | EP | disclosed |
| US-10583154-B2 | Multi-dose compositions containing an antimicrobial polyamide or octenidine preservative | Boehringer Ingelheim Animal Health USA Inc. (US) | 2020-03-10 | — | — | US | disclosed |
| EP-3442587-A1 | MULTI-DOSE COMPOSITIONS CONTAINING AN ANTIMICROBIAL POLYAMIDE OR OCTENIDINE PRESERVATIVE | Merial, Inc. (US) | 2019-02-20 | — | — | EP | disclosed |
| WO-2017180916-A1 | MULTI-DOSE COMPOSITIONS CONTAINING AN ANTIMICROBIAL POLYAMIDE OR OCTENIDINE PRESERVATIVE | MERIAL, INC. (US) | 2017-10-19 | — | — | WO | disclosed |
| US-20170296577-A1 | Multi-dose Compositions Containing an Antimicrobial Polyamide or Octenidine Preservative | MERIAL INC. (US) | 2017-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170296577-A1 | Multi-dose Compositions Containing an Antimicrobial Polyamide or Octenidine Preservative | NONO, PUF60, ERP29 | NR3C1 4859/4885HIF1A 3644/4885PGR 3418/4885 |
| US-10583154-B2 | Multi-dose compositions containing an antimicrobial polyamide or octenidine preservative | NONO, PUF60, ERP29 | NR3C1 4859/4885HIF1A 3644/4885PGR 3418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.