Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 6/20 | 0.67 |
| ▸ | PLA2G5 | P39877 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | FAAH | O00519 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | CES2 | O00748 | 5/20 | 0.58 |
| ▸ | CES1 | P23141 | 4/20 | 0.58 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2162603 | 0.83 | CES2 (0.50) | PLA2G2APLA2G5MEN1FAAHMAPK1 | |
| SCHEMBL29702819 | 0.81 | MEN1 (0.61) | PLA2G2APLA2G5MEN1FAAHMAPK1 | |
| SCHEMBL29948915 | 0.80 | PLA2G2A (1.00) | PLA2G2APLA2G5MEN1FAAHMAPK1 | |
| SCHEMBL30798618 | 0.80 | PLA2G2A (1.00) | PLA2G2APLA2G5MEN1FAAHMAPK1 | |
| SCHEMBL277126 | 0.79 | FAAH (1.00) | MEN1FAAHMAPK1KMT2ACES2 | |
| Hexadecanoic Acid Isopropylamide SCHEMBL1457147 | 0.79 | FAAH (1.00) | MEN1FAAHMAPK1KMT2ACES2 | |
| SCHEMBL19557778 | 0.79 | FAAH (1.00) | MEN1FAAHMAPK1KMT2ACES2 | |
| SCHEMBL12459875 | 0.79 | FAAH (1.00) | MEN1FAAHMAPK1KMT2ACES2 | |
| SCHEMBL4023787 | 0.79 | FAAH (1.00) | MEN1FAAHMAPK1KMT2ACES2 | |
| SCHEMBL12377250 | 0.79 | FAAH (1.00) | MEN1FAAHMAPK1KMT2ACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951058-B2 | Compound, pharmaceutically acceptable salt or optical isomer thereof, method for preparing the same, and pharmaceutical composition for prevention or treatment of viral diseases containing same as active ingredient | KATHOLIEKE UNIVERSITEIT LEUVEN K.U. LEUVEN R & D (BE) | 2018-04-24 | — | — | US | disclosed |
| US-9790197-B2 | Compound, pharmaceutically acceptable salt or optical isomer thereof, method for preparing the same, and pharmaceutical composition for prevention or treatment of viral diseases containing same as active ingredient | KATHOLIEKE UNIVERSITEIT LEUVEN K.U. LEUVEN R & D (BE) | 2017-10-17 | — | — | US | disclosed |