SCHEMBL194620

SCHEMBL194620

C=C(C)C(=O)NC(=O)CCCCCCCCC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.53
FAAH O00519 6/20 0.52
KMT2A Q03164 3/20 0.48
MEN1 O00255 2/20 0.48
MAPK1 P28482 1/20 0.48
ALDH1A1 P00352 3/20 0.46
MAPT P10636 2/20 0.46
KDM4E B2RXH2 1/20 0.46
CES2 O00748 3/20 0.45
CES1 P23141 3/20 0.45
PPARG P37231 6/20 0.43
PPARD Q03181 6/20 0.43
PPARA Q07869 6/20 0.43
HDAC11 Q96DB2 5/20 0.43
TSHR P16473 4/20 0.43
GPR84 Q9NQS5 4/20 0.43
TLR2 O60603 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
FABP4 P15090 2/20 0.43
PTPN1 P18031 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL194941 1.00 HSP90AA1 (0.53) HSP90AA1FAAHKMT2AMEN1MAPK1
SCHEMBL22491995 1.00 HSP90AA1 (0.53) HSP90AA1FAAHKMT2AMEN1MAPK1
SCHEMBL3796054 1.00 HSP90AA1 (0.53) HSP90AA1FAAHKMT2AMEN1MAPK1
SCHEMBL2926477 0.98 HSP90AA1 (0.50) HSP90AA1FAAHKMT2AMEN1MAPK1
SCHEMBL195107 0.92 ALDH1A1 (0.47) HSP90AA1FAAHKMT2AMEN1MAPK1
SCHEMBL5060564 0.90 HRH3 (0.57) FAAHKMT2AMEN1MAPTPPARG
SCHEMBL1513861 0.90 HRH3 (0.57) FAAHKMT2AMEN1MAPTPPARG
SCHEMBL31009028 0.86 HSP90AA1 (0.64) HSP90AA1FAAHKMT2AMEN1MAPK1
SCHEMBL14508042 0.84 HSP90AA1 (0.57) HSP90AA1FAAHKMT2AMEN1MAPK1
SCHEMBL194934 0.84 HDAC3 (0.46) KMT2AMEN1MAPK1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11209733-B2 Oxime ester photoinitiators BASF SE 2021-12-28 US disclosed
US-11209734-B2 Oxime ester photoinitiators BASF SE 2021-12-28 US disclosed
US-11204554-B2 Oxime ester photoinitiators BASF SE 2021-12-21 US disclosed
EP-3019473-B1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2020-02-19 EP disclosed
US-10488756-B2 Oxime ester photoinitiators BASF SE (DE) 2019-11-26 US disclosed
EP-3354641-B1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2019-07-17 EP disclosed
US-10234761-B2 Oxime ester photoinitiators BASF SE (DE) 2019-03-19 US disclosed
EP-2847167-B9 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2019-02-20 EP disclosed
EP-3354641-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2018-08-01 EP disclosed
EP-2847167-B1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2018-07-18 EP disclosed
EP-1567518-A2 OXIME ESTER PHOTOINITIATORS WITH HETEROAROMATIC GROUPS Ciba SC Holding AG (CH) 2005-08-31 EP disclosed
US-20040192804-A1 Photosensitive resin composition IGM GROUP B.V. (NL) 2004-09-30 US disclosed
US-20040170924-A1 Oxime ester photoiniators having a combined structure CIBA CORPORATION 2004-09-02 US disclosed
WO-2004050653-A2 OXIME ESTER PHOTOINITIATORS WITH HETEROAROMATIC GROUPS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-06-17 WO disclosed
EP-1395615-A1 OXIME ESTER PHOTOINITIATORS HAVING A COMBINED STRUCTURE Ciba SC Holding AG (CH) 2004-03-10 EP disclosed
US-6596445-B1 Initiators for photopolymerization of radically polymerizable compounds CIBA SPECIALTY CHEMICALS CORPORATION 2003-07-22 US disclosed
WO-2002100903-A1 OXIME ESTER PHOTOINITIATORS HAVING A COMBINED STRUCTURE CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-12-19 WO disclosed
US-20020020832-A1 Photosensitive resin composition CIBA SPECIALTY CHEMICALS CORP. 2002-02-21 US disclosed
US-20010012596-A1 For resist applications; thermostability, storage stability CIBA SPECIALTY CHEMICALS CORP. 2001-08-09 US disclosed
US-5663212-A Light-sensitive resin composition FUJI PHOTO FILM CO., LTD. (JP) 1997-09-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11209734-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 HSP90AA1 4336/4885FAAH 2595/4885KMT2A 2024/4885
US-10488756-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 HSP90AA1 4336/4885FAAH 2595/4885KMT2A 2024/4885
US-11204554-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 HSP90AA1 4349/4885FAAH 2474/4885KMT2A 2010/4885
US-10234761-B2 Oxime ester photoinitiators C9, C5, CBR3 HSP90AA1 4783/4885FAAH 1960/4885KMT2A 1256/4885
US-11209733-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 HSP90AA1 4336/4885FAAH 2595/4885KMT2A 2024/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.