SCHEMBL2926477

SCHEMBL2926477

C=C(C)C(=O)NC(=O)CCCCC

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.50
FAAH O00519 6/20 0.48
MAPT P10636 4/20 0.47
KMT2A Q03164 3/20 0.47
ALDH1A1 P00352 3/20 0.47
KDM4E B2RXH2 2/20 0.47
MEN1 O00255 2/20 0.46
MAPK1 P28482 1/20 0.46
CES2 O00748 4/20 0.43
CES1 P23141 4/20 0.43
NPSR1 Q6W5P4 1/20 0.42
PKM P14618 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
AKR1B1 P15121 1/20 0.41
TRPA1 O75762 1/20 0.41
DNM1 Q05193 1/20 0.41
TRPV1 Q8NER1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3796054 0.98 HSP90AA1 (0.53) HSP90AA1FAAHMAPTKMT2AALDH1A1
SCHEMBL194941 0.98 HSP90AA1 (0.53) HSP90AA1FAAHMAPTKMT2AALDH1A1
SCHEMBL194620 0.98 HSP90AA1 (0.53) HSP90AA1FAAHMAPTKMT2AALDH1A1
SCHEMBL22491995 0.98 HSP90AA1 (0.53) HSP90AA1FAAHMAPTKMT2AALDH1A1
SCHEMBL195107 0.94 ALDH1A1 (0.47) HSP90AA1FAAHMAPTKMT2AALDH1A1
SCHEMBL5060564 0.88 HRH3 (0.57) FAAHMAPTKMT2AMEN1NPSR1
SCHEMBL1513861 0.88 HRH3 (0.57) FAAHMAPTKMT2AMEN1NPSR1
SCHEMBL194934 0.85 HDAC3 (0.46) MAPTKMT2AALDH1A1KDM4EMEN1
SCHEMBL31009028 0.83 HSP90AA1 (0.64) HSP90AA1FAAHMAPTKMT2AALDH1A1
SCHEMBL28973344 0.82 HSP90AA1 (0.48) HSP90AA1FAAHMAPTKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7732550-B2 Stimuli-responsive polymer utilizing keto-enol tautomerization and stimuli-responsive separating material and chemical-releasing capsule comprising the same AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY MITI (JP) 2010-06-08 US disclosed
EP-0922715-B1 Stimuli-responsive polymer utilizing keto-enol tautomerization AGENCY IND SCIENCE TECHN (JP) 2008-04-02 EP disclosed
US-6858694-B2 Stimuli-responsive polymer utilizing keto-enol tautomerization and stimuli-responsive separating material and chemical-releasing capsule comprising the same AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY MITI (JP) 2005-02-22 US disclosed
US-6852819-B2 Stimuli-responsive polymer utilizing keto-enol tautomerization and stimuli-responsive separating material and chemical-releasing capsule comprising the same AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY MITI (JP) 2005-02-08 US disclosed
US-20040223947-A1 Stimuli-responsive polymer utilizing keto-enol tautomerization and stimuli-responsive separating material and chemical-releasing capsule comprising the same JNC CORPORATION (JP) 2004-11-11 US disclosed
US-20040223945-A1 Stimuti-responsive polymer utilizing keto-enol tautomerization and stimuli-responsive separating material and chemical-releasing capsule comprising the same JNC CORPORATION (JP) 2004-11-11 US disclosed
US-20020188084-A1 Stimuli-responsive polymer utilizing keto-enol tautomerization and stimuli-responsive separating material and chemical-releasing capsule comprising the same JNC CORPORATION (JP) 2002-12-12 US disclosed
EP-0922715-A2 Stimuli-responsive polymer utilizing keto-enol tautomerization AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY MITI (JP) 1999-06-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040223945-A1 Stimuti-responsive polymer utilizing keto-enol tautomerization and stimuli-responsive separating material and chemical-releasing capsule comprising the same CREB1, STIM2, GABRE HSP90AA1 2880/4885FAAH 1163/4885MAPT 114/4885
US-20040223947-A1 Stimuli-responsive polymer utilizing keto-enol tautomerization and stimuli-responsive separating material and chemical-releasing capsule comprising the same ACMSD, ADSL, CREB1 HSP90AA1 1704/4885FAAH 1057/4885MAPT 15/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.