SCHEMBL194934

SCHEMBL194934

C=C(C)C(=O)NC(=O)CCC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 3/20 0.46
HDAC1 Q13547 3/20 0.46
HDAC2 Q92769 3/20 0.46
HDAC8 Q9BY41 3/20 0.46
HDAC6 Q9UBN7 1/20 0.46
CTSD P07339 1/20 0.44
MAPT P10636 2/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
HPGD P15428 2/20 0.38
CASP2 P42575 1/20 0.38
NPC1 O15118 1/20 0.38
HTT P42858 1/20 0.38
RAB9A P51151 1/20 0.38
MAPK1 P28482 1/20 0.36
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
TGFBR1 P36897 1/20 0.35
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL195107 0.87 ALDH1A1 (0.47) MAPTMEN1KMT2ANPSR1MAPK1
SCHEMBL2926477 0.85 HSP90AA1 (0.50) MAPTMEN1KMT2ANPSR1MAPK1
SCHEMBL22491995 0.84 HSP90AA1 (0.53) MAPTMEN1KMT2AMAPK1CES2
SCHEMBL194941 0.84 HSP90AA1 (0.53) MAPTMEN1KMT2AMAPK1CES2
SCHEMBL3796054 0.84 HSP90AA1 (0.53) MAPTMEN1KMT2AMAPK1CES2
SCHEMBL194620 0.84 HSP90AA1 (0.53) MAPTMEN1KMT2AMAPK1CES2
SCHEMBL11777288 0.83 HDAC3 (0.57) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL4732318 0.82 TGFBR1 (0.39) TGFBR1ALDH1A1KDM4E
SCHEMBL194027 0.81 TGFBR1 (0.38) MAPTMEN1KMT2ANPSR1RAB9A
SCHEMBL28247132 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11209733-B2 Oxime ester photoinitiators BASF SE 2021-12-28 US disclosed
US-11209734-B2 Oxime ester photoinitiators BASF SE 2021-12-28 US disclosed
US-11204554-B2 Oxime ester photoinitiators BASF SE 2021-12-21 US disclosed
CN-107652222-B Oxime ester photoinitiators 巴斯夫欧洲公司 2021-09-10 CN disclosed
EP-3019473-B1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2020-02-19 EP disclosed
US-10488756-B2 Oxime ester photoinitiators BASF SE (DE) 2019-11-26 US disclosed
EP-3354641-B1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2019-07-17 EP disclosed
US-10234761-B2 Oxime ester photoinitiators BASF SE (DE) 2019-03-19 US disclosed
EP-2847167-B9 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2019-02-20 EP disclosed
EP-3354641-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2018-08-01 EP disclosed
EP-1395615-A1 OXIME ESTER PHOTOINITIATORS HAVING A COMBINED STRUCTURE Ciba SC Holding AG (CH) 2004-03-10 EP disclosed
US-6596445-B1 Initiators for photopolymerization of radically polymerizable compounds CIBA SPECIALTY CHEMICALS CORPORATION 2003-07-22 US disclosed
WO-2003010602-A1 PHOTOSENSITIVE RESIN COMPOSITION CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-02-06 WO disclosed
WO-2002100903-A1 OXIME ESTER PHOTOINITIATORS HAVING A COMBINED STRUCTURE CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-12-19 WO disclosed
US-20020188084-A1 Stimuli-responsive polymer utilizing keto-enol tautomerization and stimuli-responsive separating material and chemical-releasing capsule comprising the same JNC CORPORATION (JP) 2002-12-12 US disclosed
US-20020020832-A1 Photosensitive resin composition CIBA SPECIALTY CHEMICALS CORP. 2002-02-21 US disclosed
US-20010012596-A1 For resist applications; thermostability, storage stability CIBA SPECIALTY CHEMICALS CORP. 2001-08-09 US disclosed
CN-1305124-A Photosensitive resin composition CIBA SC HOLDING AG (CH) 2001-07-25 CN disclosed
EP-0922715-A2 Stimuli-responsive polymer utilizing keto-enol tautomerization AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY MITI (JP) 1999-06-16 EP disclosed
US-5663212-A Light-sensitive resin composition FUJI PHOTO FILM CO., LTD. (JP) 1997-09-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11209734-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 HDAC3 2181/4885HDAC1 2523/4885HDAC2 2426/4885
US-10488756-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 HDAC3 2181/4885HDAC1 2523/4885HDAC2 2426/4885
US-11204554-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 HDAC3 2123/4885HDAC1 2498/4885HDAC2 2388/4885
US-10234761-B2 Oxime ester photoinitiators C9, C5, CBR3 HDAC3 2811/4885HDAC1 3967/4885HDAC2 2988/4885
US-11209733-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 HDAC3 2181/4885HDAC1 2523/4885HDAC2 2426/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.