Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 6/20 | 0.49 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.45 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23777331 | 0.78 | SLC6A11 (0.47) | ALDH1A1NPSR1SLC6A1SLC6A11NPC1 | |
| SCHEMBL3931384 | 0.78 | SLC6A11 (0.48) | ALDH1A1KIF11SLC6A1SLC6A11SMN1; SMN2 | |
| SCHEMBL28349292 | 0.77 | GAA (0.43) | ALDH1A1NPSR1SLC6A1SLC6A11CTSL | |
| SCHEMBL20996163 | 0.76 | GAA (0.42) | ALDH1A1NPSR1SLC6A1SLC6A11CTSL | |
| SCHEMBL20996162 | 0.76 | GAA (0.42) | ALDH1A1NPSR1SLC6A1SLC6A11CTSL | |
| SCHEMBL21610288 | 0.76 | SLC6A11 (0.45) | ALDH1A1NPSR1SLC6A1SLC6A11NPC1 | |
| SCHEMBL1895560 | 0.76 | SLC6A11 (0.51) | KIF11SLC6A1SLC6A11 | |
| SCHEMBL16639379 | 0.75 | HDAC6 (0.45) | ALDH1A1KIF11SLC6A1SLC6A11NPC1 | |
| SCHEMBL524569 | 0.75 | SLC6A11 (0.47) | ALDH1A1NPSR1KIF11SLC6A1SLC6A11 | |
| SCHEMBL30861823 | 0.75 | SLC6A11 (0.53) | NPSR1KIF11SLC6A1SLC6A11NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10227588-B2 | 3′end caps for RNAi agents for use in RNA interference | NOVARTIS AG (CH) | 2019-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10227588-B2 | 3′end caps for RNAi agents for use in RNA interference | RNGTT, NSUN2, NSUN3 | ALDH1A1 4223/4885NPSR1 3794/4885KIF11 2009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.