SCHEMBL19463540

SCHEMBL19463540

CCCC(=O)Oc1ccc2c3c1O[C@H]1[C@@H](OC(=O)CCC)C=C[C@H]4[C@@H](C2)N(C)CC[C@@]341

nearest known ligand 0.72

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
OPRD1 P41143 10/20 0.72
OPRM1 P35372 13/20 0.65
OPRK1 P41145 11/20 0.65
MRGPRX2 Q96LB1 2/20 0.58
ADRB1 P08588 1/20 0.58
PDE4D Q08499 1/20 0.58
PDE3A Q14432 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29352353 0.92 OPRD1 (0.82) OPRD1OPRM1OPRK1MRGPRX2ADRB1
SCHEMBL16635673 0.92 OPRD1 (0.82) OPRD1OPRM1OPRK1MRGPRX2ADRB1
SCHEMBL15449784 0.91 OPRD1 (0.67) OPRD1OPRM1OPRK1MRGPRX2ADRB1
SCHEMBL28130368 0.90 OPRD1 (0.73) OPRD1OPRM1OPRK1MRGPRX2ADRB1
SCHEMBL15449783 0.90 OPRD1 (0.67) OPRD1OPRM1OPRK1MRGPRX2ADRB1
SCHEMBL3477727 0.89 OPRM1 (0.73) OPRD1OPRM1OPRK1MRGPRX2ADRB1
SCHEMBL30789045 0.88 OPRD1 (0.75) OPRD1OPRM1OPRK1MRGPRX2ADRB1
SCHEMBL21063282 0.88 OPRD1 (0.75) OPRD1OPRM1OPRK1MRGPRX2ADRB1
SCHEMBL15822773 0.88 OPRD1 (0.75) OPRD1OPRM1OPRK1MRGPRX2ADRB1
SCHEMBL15449782 0.88 OPRD1 (0.63) OPRD1OPRM1OPRK1MRGPRX2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260060822-A1 BIOENGINEERED SCAFFOLDS FOR VASCULAR GRAFTS AND METHODS OF USE THEREOF UNIV WAKE FOREST HEALTH SCIENCES (US) 2026-03-05 US disclosed
US-20250366979-A1 DEVICES AND METHODS OF MAKING AND USE THEREOF METHODIST HOSPITAL (US) 2025-12-04 US disclosed
US-20250366978-A1 DEVICES AND METHODS OF MAKING AND USE THEREOF METHODIST HOSPITAL (US) 2025-12-04 US disclosed
US-20250251323-A1 COLLECTION PROBE AND METHODS OF USE THEREOF BAYLOR COLLEGE OF MEDICINE 2025-08-07 US disclosed
WO-2025128946-A1 DEVICES AND METHODS OF MAKING AND USE THEREOF THE METHODIST HOSPITAL (US) 2025-06-19 WO disclosed
EP-4536139-A1 DEVICES AND METHODS OF MAKING AND USE THEREOF The Methodist Hospital (US) 2025-04-16 EP disclosed
EP-4536138-A1 DEVICES AND METHODS OF MAKING AND USE THEREOF The Methodist Hospital (US) 2025-04-16 EP disclosed
EP-4507825-A1 COLLECTION PROBE AND METHODS OF USE THEREOF Board of Regents, The University of Texas System (US) 2025-02-19 EP disclosed
WO-2024211329-A2 DEVICES AND METHODS OF MAKING AND USE THEREOF THE METHODIST HOSPITAL (US) 2024-10-10 WO disclosed
WO-2024044315-A1 BIOENGINEERED SCAFFOLDS FOR VASCULAR GRAFTS AND METHODS OF USE THEREOF WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) 2024-02-29 WO disclosed
WO-2023244797-A1 DEVICES AND METHODS OF MAKING AND USE THEREOF THE METHODIST HOSPITAL SYSTEM (US) 2023-12-21 WO disclosed
WO-2023244821-A1 DEVICES AND METHODS OF MAKING AND USE THEREOF THE METHODIST HOSPITAL SYSTEM (US) 2023-12-21 WO disclosed
WO-2023200850-A1 COLLECTION PROBE AND METHODS OF USE THEREOF BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-10-19 WO disclosed
US-20190328783-A1 A METHOD OF ENGINEERING PRODRUG-SPECIFIC HYPERSENSITIVE T-CELLS FOR IMMUNOTHERAPY BY GENE EXPRESSION PFIZER INC. 2019-10-31 US disclosed
EP-3429634-A1 A METHOD OF ENGINEERING PRODRUG-SPECIFIC HYPERSENSITIVE T-CELLS FOR IMMUNOTHERAPY BY GENE EXPRESSION Cellectis (FR) 2019-01-23 EP disclosed
WO-2017178586-A1 A METHOD OF ENGINEERING PRODRUG-SPECIFIC HYPERSENSITIVE T-CELLS FOR IMMUNOTHERAPY BY GENE EXPRESSION CELLECTIS (FR) 2017-10-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260060822-A1 BIOENGINEERED SCAFFOLDS FOR VASCULAR GRAFTS AND METHODS OF USE THEREOF PFKP, PBK, MYLK OPRD1 4518/4885OPRM1 4810/4885OPRK1 2862/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.