Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 6/20 | 0.40 |
| ▸ | QPCT | Q16769 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.40 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19468174 | 0.96 | NOS1 (0.40) | NOS1TBXAS1QPCTCYP1A2POLB | |
| SCHEMBL19468388 | 0.95 | NOS1 (0.39) | NOS1TBXAS1QPCTCYP1A2POLB | |
| SCHEMBL19468350 | 0.93 | CYP1A2 (0.42) | NOS1TBXAS1QPCTCYP1A2POLB | |
| SCHEMBL165635 | 0.82 | CA12 (0.45) | NOS1TBXAS1QPCTCYP1A2POLB | |
| SCHEMBL19468239 | 0.76 | TBXAS1 (0.39) | NOS1TBXAS1QPCTCYP1A2CYP3A4 | |
| SCHEMBL19468030 | 0.75 | CYP11B1 (0.49) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL6101374 | 0.72 | QPCT (0.42) | TBXAS1QPCTCYP1A2POLBCYP3A4 | |
| SCHEMBL19468373 | 0.72 | QPCT (0.36) | TBXAS1QPCTQPCTL | |
| SCHEMBL19494252 | 0.72 | NPC1 (0.55) | TBXAS1CYP1A2CYP3A4CYP2D6CYP19A1 | |
| SCHEMBL19494534 | 0.72 | CYP11B1 (0.42) | CYP1A2CYP3A4CYP2D6CYP19A1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3235815-A1 | AGENTS AGAINST PARASITIC HELMINTHS | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2017-10-25 | — | — | EP | disclosed |
| EP-3235815-A1 | AGENTS AGAINST PARASITIC HELMINTHS | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2017-10-25 | — | — | EP | disclosed |