Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 2/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.42 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.42 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17181088 | 0.84 | CA12 (0.46) | QPCTTBXAS1CYP1A2POLBCYP3A4 | |
| SCHEMBL4059533 | 0.84 | P2RX4 (0.48) | CYP3A4HCAR2FAAHMGLL | |
| SCHEMBL12490733 | 0.83 | HSD17B10 (0.33) | QPCTTBXAS1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL19468350 | 0.76 | CYP1A2 (0.42) | QPCTTBXAS1CYP1A2POLBCYP3A4 | |
| SCHEMBL23764025 | 0.75 | LMNA (0.51) | TBXAS1POLBKMT2A | |
| SCHEMBL12507096 | 0.74 | QPCT (0.36) | QPCTTBXAS1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6095146 | 0.73 | CYP3A4 (0.42) | TBXAS1CYP3A4CYP2D6CYP19A1CYP11B1 | |
| SCHEMBL19468136 | 0.72 | NOS1 (0.44) | QPCTTBXAS1CYP1A2POLBCYP3A4 | |
| SCHEMBL12490352 | 0.72 | TBXAS1 (0.42) | QPCTTBXAS1CYP1A2POLBCYP3A4 | |
| SCHEMBL1260766 | 0.72 | TBXAS1 (0.50) | QPCTTBXAS1CYP1A2POLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060094880-A9 | Synthetic process for trans-aminocyclohexyl ether compounds | BARRETT ANTHONY G M | 2006-05-04 | — | — | US | disclosed |
| US-20050038256-A1 | Synthetic process for trans-aminocyclohexyl ether compounds | CARDIOME PHARMA CORP. (CA) | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094880-A9 | Synthetic process for trans-aminocyclohexyl ether compounds | AKR1C3, CBR1, CBR3 | QPCT 2179/4885TBXAS1 279/4885CYP1A2 113/4885 |
| US-20050038256-A1 | Synthetic process for trans-aminocyclohexyl ether compounds | AKR1C3, CBR1, CBR3 | QPCT 2179/4885TBXAS1 279/4885CYP1A2 113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.