Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | QPCT | Q16769 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19468373 | 0.90 | QPCT (0.36) | TBXAS1QPCTHSD17B10 | |
| SCHEMBL13517108 | 0.84 | QPCT (0.36) | TBXAS1QPCTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL19468136 | 0.76 | NOS1 (0.44) | TBXAS1QPCTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL21578078 | 0.75 | HSD17B10 (0.36) | TBXAS1HSD17B10 | |
| SCHEMBL19468174 | 0.75 | NOS1 (0.40) | TBXAS1QPCTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL12506807 | 0.75 | ALDH1A1 (0.38) | TBXAS1 | |
| SCHEMBL12016562 | 0.74 | TBXAS1 (0.44) | TBXAS1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL12016564 | 0.74 | TBXAS1 (0.44) | TBXAS1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14464091 | 0.74 | AHR (0.31) | TBXAS1 | |
| SCHEMBL19468388 | 0.74 | NOS1 (0.39) | TBXAS1QPCTCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3235815-A1 | AGENTS AGAINST PARASITIC HELMINTHS | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2017-10-25 | — | — | EP | disclosed |
| EP-3235815-A1 | AGENTS AGAINST PARASITIC HELMINTHS | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2017-10-25 | — | — | EP | disclosed |