Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MGLL | Q99685 | 2/20 | 0.43 |
| ▸ | PHGDH | O43175 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | TSPO | P30536 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19468028 | 0.83 | TAAR1 (0.54) | ALDH1A1NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL19494605 | 0.83 | PKM (0.45) | ALDH1A1NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL19468376 | 0.82 | RAB9A (0.47) | ALDH1A1NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL19468237 | 0.81 | EPHX1 (0.47) | ALDH1A1LMNASMN1; SMN2HPGDTAAR1 | |
| SCHEMBL19468332 | 0.81 | ALDH1A1 (0.61) | ALDH1A1NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL148444 | 0.80 | MGLL (0.59) | ALDH1A1NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL19468385 | 0.79 | CYP1A2 (0.49) | ALDH1A1LMNASMN1; SMN2PKMHPGD | |
| SCHEMBL25555104 | 0.79 | ALDH1A1 (0.68) | ALDH1A1LMNAPKMHPGDMGLL | |
| SCHEMBL19468248 | 0.78 | PKM (0.44) | ALDH1A1NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL3143432 | 0.78 | MGLL (0.56) | ALDH1A1NPC1LMNARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3235815-A1 | AGENTS AGAINST PARASITIC HELMINTHS | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2017-10-25 | — | — | EP | disclosed |
| EP-3235815-A1 | AGENTS AGAINST PARASITIC HELMINTHS | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2017-10-25 | — | — | EP | disclosed |