Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.55 |
| ▸ | PHGDH | O43175 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | PKLR | P30613 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19468360 | 0.87 | MGLL (0.59) | MGLLPHGDHCA12CA1CA2 | |
| SCHEMBL19468162 | 0.84 | L3MBTL1 (0.58) | MGLLPHGDHL3MBTL1PKMPKLR | |
| SCHEMBL30064872 | 0.83 | PKM (0.59) | MGLLPHGDHCA12CA1CA2 | |
| SCHEMBL19468402 | 0.82 | PKM (0.61) | MGLLPHGDHCA12CA1CA2 | |
| SCHEMBL19468057 | 0.80 | KMT2A (0.50) | MGLLPHGDHMAPTLMNAL3MBTL1 | |
| SCHEMBL9246370 | 0.79 | KDM1A (0.49) | MGLLPHGDHCA12CA1CA2 | |
| SCHEMBL19468377 | 0.79 | PKM (0.58) | MGLLPHGDHCA12CA1CA2 | |
| SCHEMBL19494811 | 0.79 | MGLL (0.55) | MGLLPHGDHCA12CA1CA2 | |
| SCHEMBL19380430 | 0.79 | RAB9A (0.61) | MGLLPHGDHMAPTLMNAGAA | |
| SCHEMBL19468327 | 0.79 | NPC1 (0.61) | MGLLPHGDHCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3235815-A1 | AGENTS AGAINST PARASITIC HELMINTHS | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2017-10-25 | — | — | EP | disclosed |
| EP-3235815-A1 | AGENTS AGAINST PARASITIC HELMINTHS | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2017-10-25 | — | — | EP | disclosed |