Urea

Urea

SCHEMBL19468655

NC(N)=O.O=[N+]([O-])[O-].O=[N+]([O-])[O-].OO.[Zn+2]

nearest known ligand 0.46

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.46
TDP1 Q9NUW8 2/20 0.46
ALDH1A1 P00352 1/20 0.46
OR51E2 Q9H255 1/20 0.46
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
ACHE P22303 1/20 0.43
CA5A P35218 1/20 0.40
CA5B Q9Y2D0 1/20 0.40
LDHA P00338 2/20 0.38
LDHB P07195 1/20 0.38
BLM P54132 3/20 0.36
HBB P68871 1/20 0.36
HIF1A Q16665 1/20 0.36
TSHR P16473 2/20 0.35
CYP3A4 P08684 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ALOX15 P16050 1/20 0.31
PMP22 Q01453 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL19468656 0.96 LMNA (0.43) LMNATDP1ALDH1A1OR51E2MEN1
Urea SCHEMBL27486703 0.96 LMNA (0.50) LMNATDP1ALDH1A1OR51E2MEN1
Urea SCHEMBL9575581 0.88 LMNA (0.50) LMNATDP1ALDH1A1OR51E2MEN1
Urea SCHEMBL15517775 0.88 LMNA (0.50) LMNATDP1ALDH1A1OR51E2MEN1
Urea SCHEMBL28695468 0.88 LMNA (0.50) LMNATDP1ALDH1A1OR51E2MEN1
Urea SCHEMBL8523142 0.88
Urea SCHEMBL5804636 0.88
Urea SCHEMBL10483809 0.88 LMNA (0.50) LMNATDP1ALDH1A1OR51E2MEN1
Urea SCHEMBL21246922 0.88 LMNA (0.50) LMNATDP1ALDH1A1OR51E2MEN1
Urea SCHEMBL28860899 0.88 LMNA (0.50) LMNATDP1ALDH1A1OR51E2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11083201-B2 Agrichemical compositions and methods of making and using same UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) 2021-08-10 US disclosed
US-20170303543-A1 AGRICHEMICAL COMPOSITIONS AND METHODS OF MAKING AND USING SAME UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) 2017-10-26 US disclosed