Urea

Urea

SCHEMBL27486703

NC(N)=O.O=[N+]([O-])[O-].O=[N+]([O-])[O-].[Zn+2]

nearest known ligand 0.50

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.50
ALDH1A1 P00352 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
OR51E2 Q9H255 1/20 0.50
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
CA5A P35218 1/20 0.43
CA5B Q9Y2D0 1/20 0.43
TSHR P16473 2/20 0.36
CYP3A4 P08684 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ACHE P22303 1/20 0.36
BLM P54132 3/20 0.35
LDHA P00338 2/20 0.35
ALOX15 P16050 1/20 0.33
PMP22 Q01453 1/20 0.33
GAA P10253 1/20 0.32
HBB P68871 1/20 0.32
HIF1A Q16665 1/20 0.32
LDHB P07195 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL19468655 0.96 LMNA (0.46) LMNAALDH1A1TDP1OR51E2MEN1
Urea SCHEMBL19468656 0.93 LMNA (0.43) LMNAALDH1A1TDP1OR51E2MEN1
Urea SCHEMBL9575581 0.92 LMNA (0.50) LMNAALDH1A1TDP1OR51E2MEN1
Urea SCHEMBL15517775 0.92 LMNA (0.50) LMNAALDH1A1TDP1OR51E2MEN1
Urea SCHEMBL30614197 0.92 LMNA (0.50) LMNAALDH1A1TDP1OR51E2MEN1
Urea SCHEMBL10483809 0.92 LMNA (0.50) LMNAALDH1A1TDP1OR51E2MEN1
Urea SCHEMBL8523142 0.92
Urea SCHEMBL21246922 0.92 LMNA (0.50) LMNAALDH1A1TDP1OR51E2MEN1
Urea SCHEMBL5804636 0.92
Urea SCHEMBL28695468 0.92 LMNA (0.50) LMNAALDH1A1TDP1OR51E2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110818886-B Method for preparing regenerated food-grade PET polyester from waste PET polyester 中国科学院过程工程研究所 2022-02-11 CN claimed
CN-110938231-A Method for catalyzing waste PET polyester to carry out methanol alcoholysis by using eutectic solvent 中国科学院过程工程研究所 2020-03-31 CN claimed
CN-110818886-A Method for preparing regenerated food-grade PET polyester from waste PET polyester 中国科学院过程工程研究所 2020-02-21 CN claimed
CN-1192991-A Method for preparing nanometre-grade zinc oxide UNIV XIBEI (CN) 1998-09-16 CN claimed
CN-110818886-B Method for preparing regenerated food-grade PET polyester from waste PET polyester 中国科学院过程工程研究所 2022-02-11 CN disclosed
CN-112844358-A Preparation method of graphene zinc oxide nanocomposite 常州恒利宝纳米新材料科技有限公司 2021-05-28 CN disclosed
CN-109011707-B Oil-water separation material based on construction waste and preparation method thereof 江苏大学 2020-09-25 CN disclosed
CN-110938231-A Method for catalyzing waste PET polyester to carry out methanol alcoholysis by using eutectic solvent 中国科学院过程工程研究所 2020-03-31 CN disclosed
CN-110818886-A Method for preparing regenerated food-grade PET polyester from waste PET polyester 中国科学院过程工程研究所 2020-02-21 CN disclosed
CN-107175126-B Preparation method of Zn/binderless ZSM-11 molecular sieve catalyst 中国科学院大连化学物理研究所 2020-01-14 CN disclosed
CN-109011707-A A kind of water-oil separating material and preparation method thereof based on building castoff 江苏大学 2018-12-18 CN disclosed
CN-108212210-A A kind of ionic-liquid catalyst blended applied to catalytic degradation recycling polyester-cotton blend 中国科学院过程工程研究所 2018-06-29 CN disclosed
CN-105931849-A Preparation method of ZnO nanorod/nanosheet composite structure photo-anode film and photo-anode film prepared by preparation method 景德镇陶瓷大学 2016-09-07 CN disclosed
CN-105931849-A Preparation method of ZnO nanorod/nanosheet composite structure photo-anode film and photo-anode film prepared by preparation method 景德镇陶瓷大学 2016-09-07 CN disclosed
CN-104229866-B A kind of preparation method of ZnO nano porous chips cluster JIANG University OF TECHNOLOGY (CN) 2015-11-18 CN disclosed
CN-104229866-A Preparation method of ZnO nano porous sheet cluster UNIV ZHEJIANG TECHNOLOGY 2014-12-24 CN disclosed