Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Urea. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Urea SCHEMBL9239354 | 0.92 | LMNA (0.50) | — | |
| Urea SCHEMBL28860899 | 0.92 | LMNA (0.50) | — | |
| Urea SCHEMBL28695468 | 0.92 | LMNA (0.50) | — | |
| Urea SCHEMBL30614197 | 0.92 | LMNA (0.50) | — | |
| Urea SCHEMBL21246922 | 0.92 | LMNA (0.50) | — | |
| Urea SCHEMBL9575581 | 0.92 | LMNA (0.50) | — | |
| Urea SCHEMBL10483809 | 0.92 | LMNA (0.50) | — | |
| Urea SCHEMBL15517775 | 0.92 | LMNA (0.50) | — | |
| Urea SCHEMBL8523142 | 0.92 | — | — | |
| Urea SCHEMBL27586955 | 0.92 | LMNA (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113322207-B | Microbacterium XL1 and application thereof in Levan fructan production | 江苏海洋大学 | 2022-05-24 | — | — | CN | disclosed |
| WO-2006087734-A2 | A WATER SOLUBLE LAMINATION ADHESIVE | ROYCHOWDHURY SOUMEN (IN) | 2006-08-24 | — | — | WO | disclosed |
| US-5938813-A | Granular coated particles containing urea and metal nitrate, and process for making the same | SQM NITRATOS, S.A. (CL) | 1999-08-17 | — | — | US | disclosed |
| US-4460727-A | DISPERSANT IS COPOLYMER OF AMINE SALT OF ACRYLIC OR METHACRYLIC AC | DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) | 1984-07-17 | — | — | US | disclosed |