Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 3/20 | 0.44 |
| ▸ | MMP2 | P08253 | 3/20 | 0.44 |
| ▸ | MMP3 | P08254 | 3/20 | 0.44 |
| ▸ | MMP9 | P14780 | 3/20 | 0.44 |
| ▸ | MMP8 | P22894 | 3/20 | 0.44 |
| ▸ | MC4R | P32245 | 5/20 | 0.44 |
| ▸ | MC1R | Q01726 | 3/20 | 0.44 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | TSLP | Q969D9 | 3/20 | 0.40 |
| ▸ | FCGRT | P55899 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | MC5R | P33032 | 1/20 | 0.39 |
| ▸ | MC3R | P41968 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19473994 | 0.93 | FURIN (0.45) | FURINMMP1MMP2MMP3MMP9 | |
| SCHEMBL19473798 | 0.84 | MC4R (0.47) | FURINMC4RMC1RSIRT2SIRT1 | |
| SCHEMBL19473982 | 0.84 | MC4R (0.57) | MC4RMC1RTSLPMC5RMC3R | |
| SCHEMBL20206246 | 0.83 | CTSG (0.46) | FURINMC4RMC1RCTSGSIRT2 | |
| SCHEMBL19807066 | 0.82 | PIN1 (0.49) | FURINMC4RMC1RCTSGSIRT2 | |
| SCHEMBL19473973 | 0.82 | MC4R (0.58) | MC4RMC1RTSLPMC5RMC3R | |
| SCHEMBL19473902 | 0.82 | FURIN (0.47) | FURINMC4RMC1RSIRT2SIRT1 | |
| SCHEMBL19473904 | 0.82 | MC4R (0.46) | FURINMC4RCTSGSIRT2SIRT1 | |
| SCHEMBL20206279 | 0.81 | SIRT2 (0.42) | MC4RMC1RCTSGSIRT2SIRT1 | |
| SCHEMBL19474002 | 0.81 | SIRT2 (0.48) | FURINMC4RSIRT2SIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440227-B1 | MELANOCORTIN RECEPTOR-SPECIFIC PEPTIDES | PALATIN TECHNOLOGIES INC (US) | 2017-10-18 | — | — | EP | disclosed |