SCHEMBL194747

SCHEMBL194747

O=CC1C=Cc2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.38
HTR6 P50406 1/20 0.37
BRD4 O60885 1/20 0.34
CCL2 P13500 1/20 0.34
SIGMAR1 Q99720 6/20 0.34
CYP2D6 P10635 2/20 0.33
KDM4E B2RXH2 3/20 0.31
TP53 P04637 2/20 0.31
CYP3A4 P08684 2/20 0.31
HSD17B10 Q99714 2/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
PKM P14618 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
ALOX12 P18054 1/20 0.31
LMNA P02545 1/20 0.31
CHRM2 P08172 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28068535 0.98 HTR2A (0.36) HTR2AHTR6BRD4CCL2SIGMAR1
SCHEMBL28172823 0.88 SIGMAR1 (0.32) HTR2AHTR6SIGMAR1
SCHEMBL28963412 0.80 HTR6 (0.33) HTR2AHTR6BRD4CCL2SIGMAR1
SCHEMBL2514740 0.79 HTR2A (0.35) HTR2AHTR6BRD4CCL2CYP2D6
SCHEMBL547797 0.79 ALDH1A1 (0.30) CYP3A4HSD17B10ALDH1A1HPGD
SCHEMBL2951329 0.78 HTR2A (0.38) HTR2AHTR6BRD4CCL2SIGMAR1
SCHEMBL29393845 0.78 HTR2A (0.38) HTR2AHTR6BRD4CCL2SIGMAR1
SCHEMBL2364504 0.78 HTR2A (0.38) HTR2AHTR6BRD4CCL2SIGMAR1
SCHEMBL9370624 0.78 HTR2A (0.38) HTR2AHTR6BRD4CCL2SIGMAR1
Hydrochloric Acid SCHEMBL8522502 0.77 HTR2A (0.36) HTR2AHTR6BRD4CCL2SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 323 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4106822-B1 COMPOSITION COMPRISING MICRO-ENCAPSULATED MALODOR CONTROL AGENTS AND THEIR USE FOR REDUCING MALODORS HENKEL AG & CO KGAA (DE) 2024-04-17 EP claimed
EP-3800184-B1 ACETAL / KETAL-BASED FRAGRANCE AND INSECT REPELLENT PRECURSOR COMPOUNDS HENKEL AG & CO KGAA (DE) 2024-04-03 EP claimed
US-20230099941-A1 BAD-ODOR CONTROL USING ENCAPSULATION TECHNOLOGIES CONTAINING A NEUTRALIZING AGENT HENKEL AG & CO. KGAA (DE) 2023-03-30 US claimed
EP-4106822-A1 BAD-ODOR CONTROL USING ENCAPSULATION TECHNOLOGIES CONTAINING NEUTRALIZING AGENT Henkel AG & Co. KGaA (DE) 2022-12-28 EP claimed
CN-115279198-A Method for producing aromatic gas, aromatic gas and use of aromatic gas 德乐有限公司 2022-11-01 CN claimed
WO-2018145219-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING ADDICTIONS BY MEANS OF AVERSIVE COUNTERCONDITIONING SERANI MOSTAZAL JORGE (CL) 2018-08-16 WO claimed
US-10003023-B2 Display device and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-06-19 US claimed
WO-2017196762-A1 SILICONE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2017-11-16 WO claimed
US-20170301860-A1 DISPLAY DEVICE AND ELECTRONIC DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-10-19 US claimed
EP-3218425-A1 SILICONE COMPOUNDS The Procter and Gamble Company (US) 2017-09-20 EP claimed
EP-2536469-A1 STABILIZED PERFUME OILS Henkel AG & Co. KGaA (DE) 2012-12-26 EP claimed
WO-2012084292-A1 PERFUME COMPOSITION COMPRISING FRAGRANCE ALDEHYDE OR KETONE AND OXAZOLIDINE FRAGRANCE PRECURSOR HENKEL AG & CO. KGAA (DE) 2012-06-28 WO claimed
EP-2440643-A1 ODOR-IMPARTING DETERGENT, CLEANING OR CARE PRODUCT Henkel AG & Co. KGaA (DE) 2012-04-18 EP claimed
WO-2011101182-A1 STABILIZED PERFUME OILS HENKEL AG & CO. KGAA (DE) 2011-08-25 WO claimed
WO-2010142481-A1 ODOR-IMPARTING DETERGENT, CLEANING OR CARE PRODUCT HENKEL AG & CO. KGAA (DE) 2010-12-16 WO claimed
WO-2010142480-A1 ODOR-IMPARTING DETERGENT, CLEANING OR CARE PRODUCT HENKEL AG & CO. KGAA (DE) 2010-12-16 WO claimed
CN-1268636-C Dolastatin 15 derivatives ABSF AG (DE) 2006-08-09 CN claimed
CN-1264388-A Dolastatin 15 derivatives ABSF AG (DE) 2000-08-23 CN claimed
US-4727060-A HYPOTENSIVE AGENTS CIBA-GEIGY CORPORATION (US) 1988-02-23 US claimed
EP-0184550-A2 5-Amino-4-hydroxy valeryl amide derivatives CIBA-GEIGY AG (CH) 1986-06-11 EP claimed