Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | STAT6 | P42226 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1595375 | 0.88 | MAPK1 (0.31) | MAPK1TP53NFKB1CYP2C19THPO | |
| SCHEMBL5428847 | 0.79 | MAPK1 (0.42) | MAPK1TP53NFKB1CYP2C19THPO | |
| SCHEMBL28427775 | 0.71 | APLNR (0.38) | MAPK1TP53NFKB1CYP2C19THPO | |
| SCHEMBL28433495 | 0.71 | APLNR (0.38) | MAPK1TP53NFKB1CYP2C19THPO | |
| SCHEMBL6551752 | 0.71 | ALDH1A1 (0.33) | NPSR1APLNRUGT2B7 | |
| SCHEMBL11053373 | 0.69 | MAPK1 (0.32) | MAPK1TP53NFKB1CYP2C19THPO | |
| SCHEMBL3383059 | 0.67 | UGT2B7 (0.37) | MAPK1TP53NFKB1CYP2C19THPO | |
| SCHEMBL1286184 | 0.66 | TDP1 (0.35) | MAPK1TP53NFKB1CYP2C19THPO | |
| SCHEMBL2533774 | 0.66 | SLC1A2 (0.41) | MAPK1TP53NFKB1CYP2C19THPO | |
| SCHEMBL27446580 | 0.64 | SLC1A2 (0.38) | GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190135774-A1 | BIOMOLECULE PROCESSING FROM FIXED BIOLOGICAL SAMPLES | CELL DATA SCIENCES, INC. (US) | 2019-05-09 | — | — | US | disclosed |
| WO-2017184984-A1 | BIOMOLECULE PROCESSING FROM FIXED BIOLOGICAL SAMPLES | CELL DATA SCIENCES, INC. (US) | 2017-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190135774-A1 | BIOMOLECULE PROCESSING FROM FIXED BIOLOGICAL SAMPLES | UNG, POLN, POLB | MAPK1 4195/4885TP53 510/4885NFKB1 2924/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.