Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14744585 | 0.86 | TLR7 (0.56) | TLR7TLR8 | |
| SCHEMBL19180161 | 0.81 | TLR7 (0.42) | TLR7TLR8 | |
| SCHEMBL17181391 | 0.74 | TLR7 (0.45) | TLR7TLR8 | |
| SCHEMBL19475500 | 0.71 | TLR7 (0.77) | TLR7TLR8 | |
| SCHEMBL19475180 | 0.71 | ALDH1A1 (0.37) | TLR7TLR8 | |
| SCHEMBL15902487 | 0.66 | KDM4E (0.39) | TLR7 | |
| SCHEMBL1301770 | 0.65 | TLR7 (0.46) | TLR7TLR8 | |
| SCHEMBL19204368 | 0.65 | TLR7 (0.36) | TLR7TLR8 | |
| SCHEMBL9122418 | 0.64 | AGTR1 (0.58) | TLR7TLR8 | |
| SCHEMBL7997079 | 0.64 | KDM4E (0.54) | TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190127368-A1 | NLRP3 MODULATORS | IFM THERAPEUTICS INC (US) | 2019-05-02 | — | — | US | disclosed |
| US-20190127368-A1 | NLRP3 MODULATORS | IFM THERAPEUTICS INC (US) | 2019-05-02 | — | — | US | disclosed |
| WO-2017184735-A1 | NLRP3 MODULATORS | IFM THERAPEUTICS, INC (US) | 2017-10-26 | — | — | WO | disclosed |
| WO-2017184735-A1 | NLRP3 MODULATORS | IFM THERAPEUTICS, INC (US) | 2017-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190127368-A1 | NLRP3 MODULATORS | NLRP3, TLR7, TLR8 | TLR7 2/4885TLR8 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.