Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.32 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KRAS | P01116 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2091395 | 0.78 | ALDH1A1 (0.45) | ALDH1A1KDM4EGAAHPGDPOLB | |
| SCHEMBL10097951 | 0.72 | CSNK2A1 (0.39) | PNMTALDH1A1CYP1A2PYCR1CYP3A4 | |
| SCHEMBL4252113 | 0.72 | PNMT (0.57) | PNMTCYP1A2CYP2C9PYCR1DPP4 | |
| SCHEMBL1764819 | 0.72 | ALDH1A1 (0.52) | PNMTALDH1A1HPGDCYP1A2CYP2C9 | |
| SCHEMBL30812547 | 0.70 | ALDH1A1 (0.40) | PNMTALDH1A1KDM4EGLAGAA | |
| SCHEMBL3667293 | 0.69 | PNMT (0.37) | PNMTHPGDCYP1A2CYP2C9DPP4 | |
| SCHEMBL13816977 | 0.68 | CYP3A4 (0.56) | ALDH1A1KDM4EGAAHPGDCYP1A2 | |
| SCHEMBL20226102 | 0.68 | PNMT (0.38) | PNMTALDH1A1HPGDCYP1A2CYP2C9 | |
| SCHEMBL7873156 | 0.68 | KMT2A (0.53) | PNMTALDH1A1KDM4EGAAHPGD | |
| SCHEMBL20196091 | 0.65 | CYP1A2 (0.38) | PNMTALDH1A1HPGDCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190125753-A1 | COMPOUNDS AND METHODS FOR INCREASING HEMATOPOIESIS | UNIV SOUTHERN CALIFORNIA (US) | 2019-05-02 | — | — | US | disclosed |
| WO-2017184808-A1 | COMPOUNDS AND METHODS FOR INCREASING HEMATOPOIESIS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2017-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190125753-A1 | COMPOUNDS AND METHODS FOR INCREASING HEMATOPOIESIS | CTNNB1, CTNNA1, HCLS1 | PNMT 4139/4885ALDH1A1 788/4885KDM4E 3927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.