Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRND | Q07001 | 6/20 | 0.54 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.54 |
| ▸ | CHRNG | P07510 | 2/20 | 0.54 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.54 |
| ▸ | GRIA1 | P42261 | 7/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.51 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.51 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.51 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19477908 | 0.91 | CHRND (0.61) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL19477879 | 0.88 | CYP3A4 (0.50) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL23154816 | 0.86 | L3MBTL1 (0.65) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL23154665 | 0.86 | L3MBTL1 (0.65) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL23154817 | 0.86 | L3MBTL1 (0.65) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL22461945 | 0.84 | CHRND (0.47) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL15359366 | 0.84 | GRIA1 (0.46) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL16846635 | 0.82 | GRIA1 (0.46) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL8022821 | 0.82 | MMP1 (0.51) | — | |
| SCHEMBL7029376 | 0.82 | MMP1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017177326-A1 | TARGETED NUCLEIC ACID CONJUGATE COMPOSITIONS | PROTIVA BIOTHERAPEUTICS, INC. (CA) | 2017-10-19 | — | — | WO | disclosed |