Sugi Predict

Sugi Predict / Compounds / SCHEMBL1948540

SCHEMBL1948540

SCHEMBL1948540

CCCCNC(=O)CN(Cc1cccc(-c2ccccc2OCC(=O)O)c1)C(=O)OCCCC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FSHR P23945 1/20 0.46
▸ KDM4E B2RXH2 2/20 0.43
▸ FFAR1 O14842 7/20 0.42
▸ PTGDR2 Q9Y5Y4 2/20 0.42
▸ ALDH1A1 P00352 3/20 0.40
▸ HTT P42858 2/20 0.40
▸ PLA2G1B P04054 1/20 0.40
▸ L3MBTL1 Q9Y468 1/20 0.40
▸ ATG4B Q9Y4P1 1/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ GAA P10253 1/20 0.39
▸ PTPN1 P18031 2/20 0.39
▸ PPARD Q03181 1/20 0.38
▸ KMT2A Q03164 2/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ CYP1A2 P05177 1/20 0.38
▸ CYP2D6 P10635 1/20 0.38
▸ CYP2C9 P11712 1/20 0.38
▸ CYP2C19 P33261 1/20 0.38
▸ RECQL P46063 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1950346 0.91 PTGDR2 (0.47) FSHRFFAR1PTGDR2PTPN1PPARD
SCHEMBL1948087 0.90 PTGDR2 (0.47) FSHRFFAR1PTGDR2ALDH1A1HTT
SCHEMBL1946723 0.88 PTGDR2 (0.51) FFAR1PTGDR2PTPN1PPARD
SCHEMBL1947892 0.88 FFAR1 (0.43) KDM4EFFAR1ALDH1A1HTTPLA2G1B
SCHEMBL3671754 0.86 FSHR (0.47) FSHRALDH1A1GAAKMT2AMEN1
SCHEMBL1948554 0.84 FSHR (0.48) FSHRKDM4EPTGDR2ALDH1A1HTT
SCHEMBL3674765 0.81 FSHR (0.42) FSHRALDH1A1GAAGYS1
SCHEMBL3666427 0.80 FSHR (0.42) FSHRALDH1A1GAAKMT2AMEN1
SCHEMBL1948049 0.80 PTGDR2 (0.53) FFAR1PTGDR2PPARD
SCHEMBL3666582 0.79 EPHX2 (0.44) FSHRALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110136877-A1 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS LIGAND PHARMACEUTICALS INC. (US) 2011-06-09 — — US claimed
US-20110136877-A1 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS LIGAND PHARMACEUTICALS INC. (US) 2011-06-09 — — US disclosed
US-20110136877-A1 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS LIGAND PHARMACEUTICALS INC. (US) 2011-06-09 — — US disclosed
US-20110136877-A1 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS LIGAND PHARMACEUTICALS INC. (US) 2011-06-09 — — US disclosed
WO-2009089192-A1 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS LIGAND PHARMACEUTICALS INC. (US) 2009-07-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110136877-A1 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS HCAR2, PAH, PTGES2 FSHR 2819/4885KDM4E 3400/4885FFAR1 202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.