Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19481015 | 0.85 | TSHR (0.53) | TSHROPRK1HTTALDH1A1HSD11B1 | |
| SCHEMBL5401801 | 0.81 | TSHR (0.59) | TSHRHTTALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL19481016 | 0.78 | MYC (0.55) | TSHRALDH1A1L3MBTL1TP53NPC1 | |
| SCHEMBL19472428 | 0.76 | JMJD6 (0.44) | TSHROPRK1HTTALDH1A1HSD17B10 | |
| SCHEMBL17793835 | 0.76 | HCRTR1 (0.52) | TSHROPRK1HTTALDH1A1HSD11B1 | |
| SCHEMBL29551266 | 0.76 | HCRTR1 (0.52) | TSHROPRK1HTTALDH1A1HSD11B1 | |
| SCHEMBL15320488 | 0.75 | OPRK1 (0.46) | TSHROPRK1HTTALDH1A1HSD11B1 | |
| SCHEMBL29571304 | 0.75 | TSHR (0.63) | TSHRHTTALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL109206 | 0.75 | TSHR (0.63) | TSHRHTTALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL1806594 | 0.74 | DCTPP1 (0.45) | TSHROPRK1HTTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3442965-B1 | NOVEL N-[(HETEROARYLOXY)PROPANYL]HETEROARYL CARBOXAMIDES | BOEHRINGER INGELHEIM INT (DE) | 2021-05-26 | — | — | EP | disclosed |
| WO-2017178344-A1 | NOVEL N-[(HETEROARYLOXY)PROPANYL]HETEROARYL CARBOXAMIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2017-10-19 | — | — | WO | disclosed |